Advanced Pharmaceutical Solids

ISBN-13: 9780824704315 / Angielski / Twarda / 2000 / 536 str.

Jens Thur Carstensen

Opis

An exploration of the principles, instrumentation, processes and programmes of pharmaceutical solid science. It introduces aspects of one-component systems, micromeritics, polymorphism, solid-state stability, cohesion, powder flow, blending, single-unit sustained release and tablet coating.

Recenzje

"
…a comprehensive overview.
"-Pharma Times

"…would find good use as a textbook in a graduate level course on pharmaceutical solids…equally valuable as an information source for anyone seeking a brief overview of a particular area.
"-Pharmaceutical Development Technology

"…deserves a place on the bookshelves of any pharmaceutical scientist working on the development of solid dosage forms….
…an excellent initial reference for advanced students and scientists working on solids.
"-Pharmaceutical Research

Spis treści

One-Component Systems
Properties of Solids
Solubility
Particle Sizes and Diameters
Micromeritics
Crystallization
Amorphates
Polymorphism
Moisture Isotherms with Crystalline Solids
Drug Substance Considerations
Melting Point Diagrams and Eutectics
Dissolution from Particles and Surfaces
Dissolution from Polydisperse Populations
Solid-State Stability
Effect of Moisture on Solid-State Stability
Apparent Volumes and Densities
Cohesion
Powder Flow
Comminution
Blending
Wet Granulation
Hard-Shell Capsules
Tablet Physics
Physical Principles of Tablets
Disintegration and Dissolution
Polymers
Coating of Tablets
Single-Unit Sustained Release Dosage Forms
Sustained Release by Microencapsulation

O autorze

Jens T. Carstensen