Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis: Volume 2

ISBN-13: 9780306450181 / Angielski / Twarda / 1995 / 218 str.

David Z. D'Argenio

Opis

Comprises 13 chapters, arranged into four sections: pharmacokinetics, pharmacodynamics, pharmacometrics, and pharmacotherapeutics. Topics include the application of disposition decomposition analysis to metabolite kinetics; modeling multiple pharmacodynamic end points; new approaches to self-modelin

Spis treści

• Pharmacokinetics: Physiological and Biochemical Basis: Modeling of Metabolite Disposition; K.S. Pang. Application of Disposition Decomposition Analysis to Metabolite Kinetics; H. Cheng. Evaluation of Drug Interaction with Anti-HIV Nucleosides in Animal Models; M. Qian, J.M. Gallo.
• Pharmacodynamics: Models and Methods: Modeling Multiple Pharmacodynamic End Points; G.L. Rosner, P. Müller. Pharmacokinetic and Pharmacodynamic Modeling in Drug Development; H. Lemmens. Building Population Pharmacokinetic-Pharmacodynamic Models; J.W. Mandema et al..
• Pharmacometrics: Modeling and Estimation: Distribution Kinetics in the Body and Single Organisms: Moment Analysis; M. Weiss. Application of Neural Networks in Pharmacodynamics; P. Veng-Pedersen, N.B. Modi. New Approaches to Selfmodeling Nonlinear Regression; D. Verotta. EM Algorithms and Two Stage Methods in Pharmacokinetic Population Analysis; A. Schumitzky. Smoothed Pseudolikelihood Estimator for Stochastic Dynamic Systems; R. Zhang, D.Z. D'Argenio.
• Pharmacotherapy: Design and Control: Pharmacokinetic Analysis and Adaptive Control of Suramin with ADAPTII; P.R. Hutson, et al. Stochastic Control of Pharmacodynamic Processes with Application to Ergotamine; K. Park, D.Z. D'Argenio.
• Index.