Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases

ISBN-13: 9789811643910 / Angielski / Twarda / 2022 / 235 str.

Dinesh Kumar Chellappan; Kavita Pabreja; MD Faiyazuddin

Spis treści

1. Preface

2. Introduction

2.1. Nanotechnology and its influence

2.2. Novel drug delivery systems

2.3. Significance of nanomaterials in respiratory diseases

3. Nanoparticles in chronic respiratory diseases

3.1. Inflammatory respiratory diseases (Asthma, Chronic obstructive pulmonary disease, Tuberculosis, Lung cancer, Cystic fibrosis)

3.2. Formulation and role of microparticles, microspheres, microemulsions in respiratory diseases

3.3. Formulation and role of polymeric and inorganic nanoparticles

3.4. Liposomes, niosomes, and dendrimers targeting in respiratory diseases

3.5. Micelle targeting in respiratory diseases

4. Targeting immune-system/ cellular level (macrophages & neutrophils) in respiratory diseases using advanced drug delivery systems

5. Mucoadhesive drug delivery system in respiratory diseases

6. Advancement in translational respiratory research using nanotechnology

7. Nanotechnology in pulmonary disease diagnosis

8. Clinical trials using in vitro and in vivo models

9. Targeting biofilms in respiratory diseases using novel drug delivery systems

10. Future prospects and challenges

11. Bibliography

12. Glossary

 

O autorze

DineshKumarChellappan currently works at the International Medical University (IMU), Kuala Lumpur, Malaysia. He has more than 12 years of teaching experience in the current profession. He completed his Ph.D. in Pharmaceutical Sciences, from the Manipal University, India, in 2009. Prior to that, he did his Master’s in Pharmacy from the same university. He has worked on several research projects, especially in the field of diabetes and inflammation. He has published more than 1200 publications in reputed research journals with a cumulative impact factor of >2400. He also has presented a number of papers at conferences and has received research grants, both at national and international levels, to conduct research. In addition, he is a reviewer and is on the editorial board of several research journals. His area of expertise lies in the preparation of standardized plant extracts, isolation of phytoconstituents, characterization and structural elucidation of phytoconstituents, and pharmacological research of standardized extract for its various activities. 

KavitaPabreja holds a Doctoral degree in Drug Discovery Biology from Monash Institute of Pharmaceutical Sciences, Monash University, Australia. Dr Pabreja’s lecturing experience covers >5 years across national and international Universities, where she actively contributed to medical research and curriculum development. Her research experience includes >10 years of laboratory-based research focuse^21 original research and review articles in high-quality peer-reviewed journals. Currently, Dr Pabreja is utilizing her knowledge and skills in the role of Regulatory Affairs Coordinator with a leading Australian novel vaccine research company.

Md. Faiyazuddin has over 15 years of experience as an entrepreneur, academician, and researcher in the frontier areas of Pharmaceutical Sciences and Nanomedicine. Dr. Faiyazuddin is currently working as a Professor of Pharmaceutics with an additional charge of Dean Research & Development at Al - Karim University, Katihar, India. He served earlier as the Head of Asia Office and Global Business Director, Nano Drug Delivery®, Baltimore, USA. In recognition of his work, He was nominated as a Fellow member of the prestigious George Washington University USA for three years (2019 -2022). Most recently he earned ‘Executive Degree in Strategic Leadership Management’ from the Jacobs-Abbey Global Institute for Leadership Studies, USA. He holds several leading positions including Principal Investigator—Nanopharmaceutical drug delivery research lab at the Integral University, Lucknow, Assistant Professor, and Quality Coordinator—College of Pharmacy, University of Hail, KSA, and Assistant Professor, Faculty of Pharmacy, Integral University, Lucknow, India. Dr. Faiyazuddin is the founder president of the International Pharmaceutical Forum. He is an associate member of the Institute of Nanotechnology, Scotland, British Society of Nanomedicine, International Society of Aerosol in Medicine, and American Lung Association, Chicago. He has made path-breaking contributions, particularly in Drug Delivery, Respiratory Nanomedicines, Onco-pharmaceuticals, Nanoemulsions, and Nanocarriers for Skin delivery. His research has received funding from the Department of Science & Technology, Govt. of India, the Deanship of Scientific Research, UoH, Saudi Arabia, and other foreign agencies. Dr. Faiyazuddin has published more than 70 peer-reviewed manuscripts in various international journals and has authored 4 books and 7 book chapters. He has a number of awards and accolades to his name. He is the organizing member of various international conferences in the Middle East and Europe. Dr. Faiyazuddin is editor of journals like Journal of Nanomedicine and Biotherapeutic Discovery, Pharmacologia, Intellectual Property Rights: Open Access, Clinical Research, and Regulatory Affairs, International Journal of Pharmacy Teaching and Practices, International Journal of Research in Pharmaceutical and Nano Sciences, and Journal of Basic and Applied Research.

 

Blurb

This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.