Adenosine A2A Receptor Antagonists

ISBN-13: 9780443186677 / Angielski / Twarda / 2023

Jiang-Fan Chen; Akihisa Mori

Spis treści

1. A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonists Kenneth A. Jacobson 2. Chemistry - agonists, antagonists, partial agonists, inverse agonists Christa Müller 3. Functional roles of adenosine receptors - biochemistry and neuronal plasticity Ana Sebastiao 4. A2A and Depression Rodrigo Cunha 5. A2AR and glial function Zhihua Gao 6. The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signalling Rafael Franco, Gemma Navarro and Eva Martinez-Pinilla 7. How and why A2a receptor become to be a therapeutic target in Parkinson's disease therapy Peter Jenner 8. Development of A2a antagonists for Parkinson's disease - clinical evaluation for motor and non-motor symptoms Yasar Torres-Yaghi 9. The role of A2AR in chemobrain and the potential therapeutic benefits of istradefylline Detlev Boison and Mi-hyeon Jang 10. Effects of adenosine A2A receptors on cognitive function in health and disease Anna G. Orr, Cinthia Garcia and Avital Licht-Murava 11. A2a receptor and Sleep disturbance Michael Lazarus and Mustafa Korkutata 12. Adenosine A2A signals and Dystonia Makio Takahashi 13. Protective potential of caffeine and adenosine A2A adenosine receptor antagonism in LRRK2 Parkinson's disease Michael Schwarzschild 14. A2a antagonists and Alzheimer's disease David Blum 15. A2a receptors and ALS/MS Zheng Wu 16. A2AR and trauma/PTSD Yuanguo Zhou