Acromegaly

ISBN-13: 9783031162602 / Angielski / Miękka / 2023

Opis

Reviewing the most current literature, this text is a guide to medical decision-making regarding the diagnosis and treatment of patients with acromegaly. The scope of the book is comprehensive, covering all relevant facets of acromegaly, beginning with a history of the disorder and a review of the somatotrophic axis. Etiology is then discussed, including growth hormone secreting pituitary adenomas and other neuroendocrine tumors. Subsequent chapters present imaging modalities and diagnosis via radiology and clinical findings, as well as comorbid symptoms such as sleep apnea, musculoskeletal considerations, cardiovascular disorders, cancer and diabetes. Both medical and surgical management chapters describe each in detail, including radiotherapy, transsphenoidal surgery, somatostatin analogues and dopamine agonists. Concluding chapters present long-term follow-up as well as an extended selected patient story detailing life with the disease.

Bringing together the latest in endocrinologic and neurosurgical evidence and practice, Acromegaly will be the go-to resource for this challenging condition for years to come. 

Spis treści

1 Growth Hormone-secreting Pituitary Adenomas  2 Growth Hormone-secreting Neuroendocrine Tumors  3 Diagnosis of Acromegaly  4 Radiological Findings in Acromegaly  5 Clinical Presentation and Findings of Acromegaly  6 Sleep Apnea in Acromegaly  7 Cardiovascular Disorders in Acromegaly  8 Diabetes Mellitus in Acromegaly  9 Arthritis in Acromegaly  10 Malignant Disorders in Acromegaly 11 Mortality in Acromegaly  12 An Overview of the Approach to the Management of Acromegaly  13 Transsphenoidal Surgery in Acromegaly  14  Radiotherapy in Acromegaly  15 Challenging questions in the management of acromegaly in the young  16 Somatostatin Analogues in the Management of Acromegaly 17 Dopamine Agonists in the Management of Acromegaly  18 Growth Hormone Receptor Agonist Therapy in the Management of Acromegaly  19 Combination Medical Therapy in the Management of Acromegaly  20 Long-term Follow-up of Patients with Acromegaly  21 Acromegaly from the Perspective of a  Patient

O autorze

Lewis S. Blevins Jr., MD, Department of Neurological Surgery, California Center for Pituitary Disorders and Brain Tumor Center, University of California - San Francisco, San Francisco, CA, USA

Manish Aghi, MD, PhD, Department of Neurological Surgery, California Center for Pituitary Disorders and Brain Tumor Center, University of California - San Francisco, San Francisco, CA, USA