A Common Pathway Drug Design for all types of Cardiovascular Diseases : A Network Biology Approach

ISBN-13: 9786200251794 / Angielski

Al - Mustanjid; Md. Habibur Rahman; Chandan Mandal

Opis

Cardiovascular diseases are becoming a key concern globally over an era across all non-communicable diseases. Cardiovascular diseases have been occurring around the world due to some widespread risk variables. Diseases have such a genetic association emerging from equivalent risk factors, either indirectly or directly. If a gene loses its normal activity and adversely affects the body a disease is caused. Currently, it is observed that the inability of a disease through the protein-protein interaction is more fruitful than the single gene. Multiple scientific studies have uncovered tactics to use advanced Bioinformatics strategies and tools in network biology to construct a structure-based drug from crucial biomolecule or protein for diseases. This study determines the protein-protein interaction network and designs a common pathway drug for all types of cardiovascular diseases. The data mining application called knowledge discovery in database has been performed and genes are filtered, pre-processed, converted and mined to locate common genes for all types of cardiovascular diseases. To accomplish the goal, Unihi is used as a tool.

O autorze

Mustanjid, Al -
Al - Mustanjid was born in Bangladesh and he is an expert in Network Biology. He has research interest in Bioinformatics, Software Development Life Cycle (SDLC), Data Mining and Statistical Analysis.