A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis

ISBN-13: 9781439835272 / Angielski / Miękka / 2010 / 236 str.

Franz Joel Leong;Veronique Dartois;Thomas Dick

Opis

An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientists, and doctors working, learning, and teaching in the field of TB. It contains 100 color photographs and illustrations that bring clarity to the information presented. The atlas takes the unusual approach of covering multiple species histopathology, arguably the first and quite possibly the only resource to do so. It provides a simple, annotated, and visual presentation of the comparative histopathology of TB in human and animal models. The editors have compiled information that helps TB scientists to distinguish between the features of all major animal models available and to use them with their strengths and limitations in mind. The book provides guidance for selecting the best animal model(s) to answer specific questions and to test the efficacy of drug candidates.

Recenzje

"This book is an excellent introduction to pulmonary tuberculosis and the physiologic, pathologic, and political hurdles as to why it has been such a difficult disease to contend with. The authors explain the intricacies of the tuberculin bacterium, the host defenses, and the theories behind current treatment modalities.
The atlas is designed as a concise resource for researchers working in the field and the laboratory to evaluate the pulmonary pathologic response to the Mycobacterium organism and design more successful treatment and disease eradication for human and animal species. The multitude of photomicrographs and gross pathology photographs are of excellent quality and well-labeled. The text is well written, organized in an easy to read format, and well-referenced for further research."
—Sandra L. Jex, DVM, in alnmag.com

Spis treści

Introduction to Tuberculosis. Tuberculosis Drug Discovery and the Role of Animal Models. Basic Histology of Human Lung. Histopathological Manifestations of Pulmonary Tuberculosis in Humans. Pulmonary Tuberculosis in Monkey. Pulmonary Tuberculosis in Rabbit. Pulmonary Tuberculosis in Guinea Pig. Pulmonary Tuberculosis in Rat. Pulmonary Tuberculosis in Mouse.

O autorze

Franz Joel Leong, Veronique Dartois, Thomas Dick