Arterial Chemoreceptors

ISBN-13: 9789048122585 / Angielski / Twarda / 2009 / 455 str.

Constancio Gonzalez; Colin A. Nurse; Chris Peers

Opis

This volume contains the Proceedings of the XVIIth ISAC Meeting held in Valladolid, Spain, July 1-5, 2008. As such, it contains the most permanent records of the combined efforts of all attendants. The meeting was held at the School of Medicine of Valladolid, that had the privilege of a recent celebration. The celeb- tion was none other than its 600th anniversary, implying that all participants were surrounded by historical landmarks, from the historical building of the University, to the Museum of polychrome sculpture of Valladolid, to the Monastery of Clarisas in Tordesillas, to the beauty and charm of Salamanca. In this ambience we had three days of intense work, distributed in several oral sessions, preceded by plenary lectures given by our invited speakers who were kind enough to provide us with the latestprogressintheirspeci c elds. We also hadtimeallottedtoposterviewing. As regularattendantsto the XVIIth ISACMeeting, we want to expressourappreciation forthevaluablediscussionssurroundingeachposter, theenthusiasticpresentationof data, the comments of colleagues with suggestions for improvement, and the plans for collaborations that emerged from these discussions. Needless to say that XVIIth ISAC Meeting was the fruit of many collabo- tive efforts. The Local Organizing Committee pro ted from the advice of several colleagues from around the world, namely, Prof. Chris Peers from Leeds, UK, Prof. Prem Kumar from Birmingham, UK, Prof. Nanduri Prabhakar from Chicago, USA, Prof. Colin Nurse from Hamilton, Canada, and Prof. Rodrigo Iturriaga from Santiago, Chile

Spis treści

The Discovery of Sensory Nature of the Carotid Bodies. Invited Article; F. De Castro. Fifty Years of Progress in Carotid Body Physiology. Invited article; R. S. Fitzgerald, C. Eyzaguirre and P. Zapata. Carotid Body: New Stimuli and New Preparations. Invited article; Colin A. Nurse. Enzyme-Linked Acute Oxygen Sensing In Airway And Arterial Chemoreceptors. Invited article; Paul J Kemp & C Peers. Cysteine Residues in the C-terminal tail of the Human BKCaa Subunit are Important for Channel Sensitivity to Carbon Monoxide; S.P. Brazier, V. Telezkhin, R. Mears, C.T. Müller, D. Riccardi and P.J. Kemp. Modulation of O2 Sensitive K+ Channels by AMP-activated Protein Kinase; M.L Dallas, J.L Scragg, C.N. Wyatt, F. Ross, D.G Hardie, A.M Evans and C Peers. Hydrogen Sulfide Inhibits Human BKCa Channels; V. Telezhkin, S. P. Brazier, S. Cayzac, C. T. Müller, D. Riccardi and D P. J. Kemp. DPPX Modifies TEA Sensitivity of the Kv4 Channels in Rabbit Carotid Body Chemoreceptor Cells; O. Colinas, F.D. Pérez-Carretero, E. Alonso, J.R. López-López and M. T. Pérez-García. Sustained Hypoxia Enhances TASK-like Current Inhibition by Acute Hypoxia in Rat Carotid Body Type-I Cells; F. Ortiz, R. Iturriaga and R. Varas. Inhibition of L-type Ca2+ Channels by Carbon Monoxide; M.L. Dallas, J.L. Scragg and C. Peers. Effects of the Polyamine Spermine on Arterial Chemo-Reception; S. Cayzac, A. Rocher, A. Obeso, C. González, P.J. Kemp and D. Riccardi. RT-PCR and Pharmacological Analysis of L-and T-Type Calcium Channels in Rat Carotid Body; A.I. Cáceres, E. González-Obeso, C. González and A. Rocher. Functional characterization of phosphodiesterases 4 in the rat carotid body: effect of oxygen concentrations; A.R. Nunes, J.R. Batuca and E.C. Monteiro. Calcium sensitivity for hypoxia in PGNs with PC-12 cells in co-culture; Patel GP, Baby SM, Roy A, Lahiri S. Modification of relative gene expression ratio obtained from real time qPCR with whole carotid body by using mathematical equations;J.H. Kim, I. Kim, and J.L. Carroll. Neurotransmitters in Carotid Body Function: The Case of Dopamine. Invited article; R. Iturriaga, J. Alcayaga, and C. González. Adenosine in peripheral chemoreception: new insights into a historically overlooked molecule. Invited article; S. V. Conde, E.C. Monteiro, A. Obeso and C. Gonzalez. The A2B-D2 receptor interaction that controls carotid body catecholamines release locates between the last two steps of hypoxic transduction cascade; S. V. Conde, A. Obeso, Monteiro EC. and C. Gonzalez. Benzodiazepines and GABA-GABAA Receptor System in the Cat Carotid Body; A. Igarashi, N. Zadzilka, M. Shirahata. Evidence For Histamine As a New Modulator of Carotid Body Chemoreception; R. Del Rio, E.A. Moya, J. Alcayaga and R. Iturriaga. Fluoresceinated Peanut Agglutinin (PNA) is a Marker for Live O2 Sensing Glomus Cells in Rat Carotid Body; I. Kim, D.J. Yang, D.F. Donnelly and J.L. Carroll. Neuroglobin in Aging Carotid Bodies; V. Verratti, C. Di Giulio, G. Bianchi, M. Cacchio, G. Petruccelli, C. Di Giulio, L. Artese, S. LahiriI and R. Iturriaga. Oxygen sensing and the activation of the Hypoxia Inducible Factor 1 (HIF-1). Invited article; Joachim Fandrey1 & Max Gassmann2 .Upregulation of Erythropoietin and its Receptor Expression in the Rat Carotid Body during Chronic and Intermittent Hypoxia; S.Y. Lam, G.L. Tipoe, and M.L. Fung. Iron Chelation and the Ventilatory Response to Hypoxia; Mieczyslaw Pokorski, Justyna Antosiewicz, Camillo, Di Giulio, and Sukhamay Lahiri. Systemic Effects Resulting From Carotid Body Stimulation Invited article; Prem Kumar. Bicarbonate-Regulated Soluble Adenylyl Cyclase (sAC) mRNA Expression and Activity in Peripheral Chemoreceptors; A. R. Nunes, E. C. Monteiro, S. M. Jonhson,E. B. Gauda. Developmental Maturation of Chemosensitivity to Hypoxia of Peripheral Arterial Chemoreceptors. Invited article; Estelle B. Gauda, John L. Carroll, David F. Donnelly. Physiological Carotid Body Denervation During Aging; C. Di