THEORETICAL MODEL OF THE PATHOPHYSIOPATHOGENESIS OF AUTOALLERGIES

ISBN-13: 9786204903026 / Angielski / Miękka / 52 str.

Carlos Parga-Lozano; Maria Bertel; Kelly Yaspe

Opis

Autoimmune diseases and type I hypersensitivity diseases have been handled in isolation from the pathophysiological point of view. But it is important to identify the union between these two fields of Immunology and to identify a model that combines them, since there is no clarity in the mechanisms that lead to autoallergies as a unitary disease. Within the different types of existing immune responses, there is a small group, where the main characteristic is that the individual's immune system loses the capacity to differentiate the self from the foreign, thus generating responses directed to self antigens. On the other hand, there are the type (I) hypersensitivity responses that occur in atopic individuals after a short time of exposure to an external allergen, resulting in an excessive and disproportionate response that causes tissue damage.

O autorze

Parga-Lozano, CarlosPhD and Master in Immunology Universidad Complutense de Madrid. Member of the Spanish Society of Immunology. Member of the National Cancer Network, National Cancer Institute. Senior Researcher, Ministry of Science, Technology and Innovation.