Carbohydrate Metabolism in Pregnancy and the Newborn 1978

ISBN-13: 9783540087984 / Angielski / Miękka / 1979 / 540 str.

H. W. Sutherland; J. M. Stowers

Opis

This book assembles present knowledge of the different aspects of human reproduction complicated by diabetes. The contributions are based on the Fourth Quinquennial Aberdeen Colloquium held in 1988 and update the results of the three previous meetings. Many new topics are covered, such as maternal nutrition, obesity, infertility, abortion, retinopathy, and so forth. Care has been taken to include clinical practice guidelines and protocols for the management of diabetic pregnancy and the infant of the diabetic mother. The book is, therefore, designed as much to suit the practicing clinician as the specialist or research worker wishing to keep abreast of contemporary knowledge that has been collected, collated and distilled by internationally recognized experts.

Spis treści

Speakers at the 2nd Aberdeen Colloquium IX.- Foreword XI11.- Preface XV.- 1 Realignments of Metabolism.- 1.1 Intermediary Metabolism During Normal Pregnancy.- 1.2 Metabolic Changes in Pregnancy Relevant to Diabetes.- 1.3 Insulin Response Studies in Normal Pregnancy and Chemical Gestational Diabetes.- 2 Placental Structure Function and Blood Flow.- 2.1 Utero-Placental Blood Supply in Maternal Diabetes..- 2.2 Placental Handling of Glucose.- 2.3 Utero-Placental Blood Flow. Methods of Determination, Clinical Application and the effect of Beta-Mimetic Agonists.- 2.4 Placental Changes in Gestational Diabetes.- 3 Endocrine Pancreas.- 3.1 The Maternal Endocrine Pancreas.- 3.2 Amino Acids and Development of the Beta Cell.- 3.3 The Relationship Between Glucagon and Hypocalcaemia in Infants of Diabetic Mothers.- 3.4 Pregnancy Related Factors Affecting Insulin Secretion.- 4 Fetal Nutrition and Macrosomia.- 4.1 Experimental Contributions to the Physiology of Fetal Macrosomia.- 4.2 Heavy-for-Dates Babies.- 4.3 Controlling Factors of Fetal Nutrition.- 5 Fetal Anomalies Related to Metabolism.- 5.1 Fetal Anomalies Related to Carbohydrate Metabolism: The Epidemiological Approach.- 5.2 Experimental Evidence Relating Fetal Anomalies to Diabetes.- 5.3 Congenital Malformations in Newborns of Diabetic Mothers.- 6 Antenatal Fetal Monitoring.- 6.1 Evaluation of Placental Steroids in Diabetic Pregnancy.- 6.2 Fetal Assessment in Diabetic Pregnancy Using Non-steroid Assessments.- 6.3 Management of the Pregnant Diabetic - When and How to Deliver.- 6.4 The Role of Pregnancy-Specific B1-Glycoprotein in the Management of Pregnancies Complicated by Diabetes.- 7 Symptomatic Diabetes.- 7.1 Management of Maternal Diabetes in Pregnancy.- 7.2 Sulphonylureas for Chemical Diabetes in Pregnancy.- 7.3 Management of Diabetes During Delivery with an Artificial Pancreas.- 7.4 Neonatal Problems.- 7.5 Preterm Labour and Perinatal Mortality in Diabetic Pregnancy - Obstetric Considerations.- 8 Asymptomatic Diabetes.- 8.1 Asymptomatic Diabetes in Pregnancy.- 8.2 Gestational Diabetes: Factors Influencing the Rates of Subsequent Diabetes.- 8.3 Detection of Chemical Gestational Diabetes.- 8.4 Qualitative Assessment of Children of Known Gestational Diabetec Mothers.- 9 Maternal Weight.- 9.1 Reproduction in Obese Women.- 9.2 Weight and Weight Gain in Pregnant Women.- 9.3 Glucose Tolerance in Complicated Pregnancies.- 9.4 Dieting in Pregnancy. A Study of the Effect of a High Protein Low Carbohydrate Diet on Birthweight on an Obstetric Population.