This comprehensive book addresses all elements of the autonomic nervous system (ANS) and sleep interaction, as well as ANS alterations in sleep and how these impact primary and comorbid sleep dysfunction. It meets the market need for a comprehensive text that deals with ANS changes in sleep and how these impact various neurological, medical, and primary sleep disorders.
Organized into three parts, the book begins with a review of the foundational bodily systems that participate in coordination of ANS activity with other homeostatic responses such as respiration, cardiovascular reflexes, and responses to stress. Part two then examines methods of laboratory evaluation and the “why, when, how” of interpreting heart rate variability in sleep. To conclude, the final section of the book broadly covers the many clinical aspects of ANS, including insomnia, restless leg syndrome, sleep apnea, sleep related epilepsy, and acute autonomic neuropathy.Autonomic Nervous System and Sleep enhances the reader's understanding of the pathophysiology of various disorders, and explains how to apply this profound understanding is important to new lines of therapy to improve morbidity.
Afferent and efferent Autonomic Nervous Systems (including Sympathetic, Parasympathetic, and Enteric Nervous systems)
Functional neuroanatomy of Sleep
Physiological changes in ANS during sleep
Brain-heart interaction: cardiovascular reflexes (including Baroreceptor reflex and Baroreceptor sensitivity in sleep)
Homeostatic and Circadian regulation of ANS and Sleep
Nocturnal arousal phenomenon and the ANS
Section II: Laboratory Assessment
Laboratory Assessment of ANS: Synopsis of the tests
Method of Laboratory Evaluation of ANS in Wakefulness and Sleep
Heart rate Variability (HRV) in normal and abnormal sleep
Laboratory Evaluation of Sleep Disorders: PSG, MSLT, MWT, Actigraphy
Section III: Clinical Aspects
An approach to a patient with suspected Autonomic failure and sleep dysfunction
Classification of Autonomic failure with sleep dysfunction
Disorders of the Autonomic Nervous System and Sleep Dysfunction
Autonomic overactivity and Primary Sleep Disorders
Autonomic overactivity and neurological or general medical condition associated with sleep disorders
Autonomic failure and Primary Sleep Disorders
Autonomic failure and neurological or general medical condition associated with sleep disorders
Sudhansu Chokroverty, MD
Hackensack Meridian Health
Neuroscience Institute at JFK
JFK University Medical Center
Seton Hall University & Hackensack Meridian
School of Medicine at Seton Hall
Rutgers Robert Wood Johnson Medical School
New Jersey, USA
Pietro Cortelli, MD, PhD
IRCCS Istituto di Scienze Neurologiche
Department of Biomedical
NeuroMotor Sciences
University of Bologna
Bologna, Italy
This comprehensive book addresses all elements of the autonomic nervous system (ANS) and sleep interaction, as well as ANS alterations in sleep and how these impact primary and comorbid sleep dysfunction. It meets the market need for a comprehensive text that deals with ANS changes in sleep and how these impact various neurological, medical, and primary sleep disorders.
Organized into three parts, the book begins with a review of the foundational bodily systems that participate in coordination of ANS activity with other homeostatic responses such as respiration, cardiovascular reflexes, and responses to stress. Part two then examines methods of laboratory evaluation and the “why, when, how” of interpreting heart rate variability in sleep. To conclude, the final section of the book broadly covers the many clinical aspects of ANS, including insomnia, restless leg syndrome, sleep apnea, sleep related epilepsy, and acute autonomic neuropathy.
Autonomic Nervous System and Sleep enhances the reader's understanding of the pathophysiology of various disorders, and explains how to apply this profound understanding is important to new lines of therapy to improve morbidity.