The Spectrum of Risk Lesions in Breast Pathology: Risk Factors or Cancer Precursors?.- Lobular Carcinoma In Situ: Risk Factor or Cancer Precursor?.- Ductal Carcinoma In Situ: Risk Factor or Cancer.- Diagnostic Management of Papillomas, Radial Scars, and Flat Epithelial Atypia: Core Biopsy Alone Versus Core Biopsy Plus Excision.- Diagnostic Management of Fibroepithelial Lesions: When Is Excision Indicated?.- Diagnostic Management of the Atypical Hyperplasias: Core Biopsy Alone vs Excisional Biopsy.- Diagnostic management of LCIS: Core biopsy alone versus core biopsy plus excision for classic versus pleomorphic LCIS.- Breast Cancer Risk Prediction in Women with Atypical Breast Lesions.- Advanced Screening Options and Surveillance in Women with Atypical Breast Lesions.- The Role of Chemoprevention in the Prevention of Breast Cancer.- Prophylactic Mastectomy in Patients with Atypical Breast Lesions.- The Non-surgical Management of Ductal Carcinoma in Situ (DCIS).- Surgical Treatment of Ductal Carcinoma in Situ.
Farin Amersi, MD Associate Professor of Surgery Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute 8700 Beverly Blvd, #AC1046A Los Angeles, CA, 90048, USA
Kristine Calhoun, MD Associate Professor of Surgery University of Washington School of Medicine Associate Director, Breast Health Clinic, Seattle Cancer Care Alliance 1959 NE Pacific Street, Box 356410 Seattle, WA, 98195, USA
The days of surgical excision for any atypical lesion have been replaced by more nuanced decision making and individualized patient management. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion.
The goal of this book is to provide a concise but comprehensive review of atypical breast proliferative lesions and their management complexities. New data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions are discussed in full detail. Assessment tools for risk prediction of breast cancer are also highlighted as chapters run the gamut of current imaging modalities, as well as advanced screening options available for diagnosis and following these patients.
Atypical Breast Proliferative Lesions and Benign Breast Disease will undoubtedly become a valuable resource for nurse practitioners, physician assistants, breast and surgical oncology fellows, genetic counselors, geneticists, as well as other clinicians and surgeons who are referred and manage these complex breast patients. All chapters in this text are written by experts in the field who have research and clinical interest in each of these disease entities, and include the most up-to-date research and clinical information to enhance our understanding and treatment of patients.