Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications

ISBN-13: 9781617371202 / Angielski / Miękka / 2010 / 188 str.

Carolina M. Maier; Gary K. Steinberg

Opis

A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia as a neuroprotective strategy in the treatment of stroke and traumatic brain injury. Topics of special importance include intraoperative and intensive care management of hypothermia-treated patients, a critical look at the potential for combining hypothermia with pharmacotherapy, and an update on the latest technological advances that have made hypothermic treatment possible in today's clinical setting.

Recenzje

"...a highly relevant volume for clinicians and basic scientists alike in the field of cerebral ischemia research and care...I recommend this book to most health science-related libraries, institutions, and individuals with significant interests in the research and treatment of patients with stroke and TBI." - J. Neurosurg.

"...contains a plethora of up-to-date and important information on both basic and clinical research. It is worthwhile to recommend as a reference book for the student, scientist and physician who is interested in or involved in the study of mild hypothermia for the treatment of stroke and traumatic brain injury." - Canadian Journal of Neurological Sciences

"This book is an easily understood 'snap shot' of the current state of knowledge." - Can J Anesth

Spis treści

Resurgence of Hypothermia as a Treatment for Brain Injury Carolina M. Maier and Gary K. Steinberg The Effects of Hypothermia and Hyperthermia in Global Cerebral Ischemia Myron D. Ginsberg and Ludmila Belayev Mild Hypothermia in Experimental Focal Cerebral Ischemia Carolina M. Maier Hypothermic Protection in Traumatic Brain Injury W. Dalton Dietrich and Miguel A. Pérez-Pinzón Postischemic Hypothermia Provides Long-Term Neuroprotection in Rodents Frederick Colbourne and Dale Corbett Combination Therapy With Hypothermia and Pharmaceuticals for the Treatment of Acute Cerebral Ischemia David C. Tong and Midori A. Yenari Intraoperative and Intensive Care Management of the Patient Undergoing Mild Hypothermia Teresa E. Bell-Stephens, Richard A. Jaffe, and Gary K. Steinberg Management of Traumatic Brain Injury With Moderate Hypothermia Elad I. Levy and Donald W. Marion Hypothermia: Clinical Experience in Stroke Patients Stefan Schwab and Werner Hacke Hypothermia Therapy: Future Directions in Research and Clinical Practice Wataru Kakuda, Takao Shimizu, and Hiroaki Naritomi. Index.

Blurb

Hypothermia is one of the most effective neuroprotective therapies in experimental ischemia modes, and there is widespread interest in using it to treat stroke and traumatic brain injury (TBI) patients. In Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications, leading investigators and pioneers from around the world take hypothermia from bench to bedside, comprehensively reviewing both the scientific and clinical studies that have led to its resurgence in the treatment of stroke. Topics of special interest include intraoperative and intensive care management of hypothermia-treated patients, a critical look at the potential for combining hypothermia with pharmacotherapy, and an update on the latest technological advances that have made hypothermic treatment of stroke and TBI possible in the current clinical setting. The authors also comprehensively review mild hypothermia's therapeutic potential and limitations, the latest developments in both basic and clinical hypothermia research, and actual clinical experience with hypothermia in stroke and TBI patients.
Comprehensive and up-to-date, Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications summarizes for clinicians and basic scientists alike all that is known about the use of hypothermia as a neuroprotective strategy in the treatment of today's stroke and TBI patients.