Molecular Mechanisms Involved in the Pathogenesis of Huntington's Disease

ISBN-13: 9781617289712 / Angielski / Miękka / 2011 / 56 str.

Claudia Perandones;Federico Eduardo Micheli;Martín Radrizzani

Opis

Huntington's disease (HD) is an autosomal-dominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea, incoordination, cognitive decline, and behavioural difficulties. This book focuses on HD, outlining the effects of mutant htt in the nucleus and cytoplasm, the role of cell-cell interactions in the HD pathology.