Hydroxyapatite: Synthesis and Applications

ISBN-13: 9781606506738 / Angielski / Miękka / 2014 / 220 str.

Yoshiki Oshida

Opis

Hydroxyapatite (HA) is the primary material of natural bone and teeth--and the subject of much intense research in recent years for new variants with special functional properties for biomedical engineering applications. It is a naturally occurring mineral form of calcium apatite, with the formula Ca10(PO4)6(OH). The OH- ion can be replaced by fluoride, chloride or carbonate, producing fluorapatite or chlorapatite. HA makes up bone mineral and the matrix of teeth, giving both their rigidity and durability, and has been widely used in medical/dental field as bone grafting material, bone cement material, and as an effective additive material for surface coating. This book will cover the essential physical and chemical structure of HA and offer the reader the latest research and applications, particularly with regard to functionalizing HA and using it as a matrix for biomimeticazation for bone and dental repair.

Evidence-based literature reviews can provide foundation skills in research-oriented bibliographic inquiry, with an emphasis on such review and synthesis of applicable literature. Information is gathered by surveying a broad array of multidisciplinary research publications written by scholars and researchers. This book is based on a review of about 2,000 carefully selected articles about hydroxyapatite (HA) materials from about 150 peer-review journals in both engineering and medical areas and presents itself as a typical example of evidence-based learning (EBL). HA is very unique material which has been employed equally in both engineering and medical and dental fields. In addition, the name "apatite" comes from the Greek word ????w, which means to deceive. What is actually happening inside the apatite crystal structure is based on the unique characteristics of ion exchangeability. Because of this, versatility of HA has been recognized in wide ranges, including bone-grafting substitutes, various ways to fabricate HAs, HA-based coating materials, HA-based biocomposites, scaffold materials, and drug-delivery systems. This book covers all these interesting areas involved in HA materials science and technology.