Antimutagenesis and Anticarcinogenesis Mechanisms II

ISBN-13: 9781461595632 / Angielski / Miękka / 2012 / 493 str.

Yukioki Kuroda; Delbert M. Shankel; Michael D. Waters

Recenzje

From Book News, Inc.
The papers are arranged in eight sections, addressing: antimutagens in food; antimutagens and anticarcinogens in environmental toxicology; free radicals; antitumor initiators; antitumor promoters; aspects of mammalian and human genetics; molecular aspects of mutagenesis and antimutageneis; and oncogenes and antioncogenes.
Annotation copyright Book News, Inc. Portland, Or.

Spis treści

Antimutagenesis Studies in Japan.- Cancer Prevention: Underlying Principles and Practical Proposals.- Antimutagens in Food.- Anticlastogenic Dietary Factors Assessed in Mammalian Assays.- Antigenotoxic Activity of Carotenoids in Carcinogen-Exposed Populations.- Plant Antimutagens.- Antimutagens and Anticarcinogens in Environmental Toxicology.- Human Biomonitoring in Exposure to Environmental Genotoxicants.- The Concept of Activity Profiles of Antimutagens.- Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain.- Free Radicals.- Free Radical Reactions with DNA and its Nucleotides.- Mechanisms of Inactivation of Oxygen Radicals by Dietary Antioxidants and their Models.- Role of Dietary Antioxidants in Protection Against Oxidative Damage.- Antitumor Initiators And Carcinogenesis.- Inhibition of Carcinogenesis by Naturally-occurring and Synthetic Compounds.- Newly Recognized Anticarcinogenic Fatty Acids.- Caloric Restriction in Experimental Carcinogenesis.- Carcinogenicity and Modification of Carcinogenic Response by Antioxidants.- Antitumor Promoters and Carcinogenesis.- Inhibition of Tumor Promotion by DL-?-Difluoromethyl-Ornithine, A Specific Irreversible Inhibitor of Ornithine Decarboxylase.- New Antitumor Promoters: (-)-Epigallocatechin Gallate and Sarcophytols A and B.- Chemoprevention of Mammary Cancer by Retinoids.- Aspects Of Mammalian And Human Genetics.- Suppression of Tumor Promotion by Inhibitors of Poly(ADP)ribose Formation.- Antimutagenic Activity of Vitamins in Cultured Mammalian Cells.- Microcell-Mediated Chromosome Transfer: A Strategy for Studying the Genetics and Molecular Pathology of Human Hereditary Diseases with Abnormal Responses to DNA Damage.- Molecular Aspects Of Mutagenesis And Antimutagenesis.- Genetic Analyses of Cellular Functions Required for UV Mutagenesis in Escherichia coli.- Position of a Single Acetylaminofluorene Adduct within a Mutational Hot Spot is Critical for the Related Mutagenic Event.- Fidelity of Animal Cell DNA Polymerases ? and ? and of a Human DNA Replication Complex.- Molecular Mechanisms of Replicational Fidelity in Escherichia Coli.- Oncogenes And Antioncogenes.- Permanent Conversion of NIH3T3 Cells Transformed by Activated c-Ha-ras, c-Ki-ras, N-ras, OR c-raf, and of Human Pancreatic Adenocarcinoma Containing Activated c-Ki-ras to Apparently Normal Cells by Treatment with the Antibiotic Azatyrosine.- Oncogenes of Stomach Cancers.- Oncogenic Potential and Normal Function of the Proto-oncogenes Encoding Protein-Tyrosine Kinases.- Short Papers.- Inhibition of the Genotoxicity of 3-Amino-1-Methyl-5H- Pyrido[4,3-b]Indole (Trp-P-2) in Drosophila by Chlorophyll.- Inhibition of Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK)-Induced Lung Tumors and DNA Methylation in F344 Rats and A/J Mice by Phenethyl Isothiocyanate.- Proteolytic Activation of UmuD and MucA Proteins for SOS Mutagenesis.- Analysis of Bleomycin-resistant DNA Synthesis in Cells from an Inherited Human Disorder, Ataxia Telangiectasia.- Tumor Dose-response Studies with Aflatoxin B1 and the Ambivalent Modulator Indole-3-carbinol: Inhibitory versus Promotional Potency.- Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin.- The Use of Drosophila as an in VIVO System to Study Modifiers of Chemical Mutagenesis.- The Mouse Mutant, “Wasted”: Tissue-specific Radiation Sensitivity and Hematopoietic Cell Lineages.- Antimutagenic Effects of Tumor Promoters—Co-mutagenic Effects of Co-carcinogens.- Antimutagenic Effects of Dimethyl Sulfoxide on Metabolism and Genotoxicity of Benzene in Vivo.- Possible Antitumor Promoter in the Glandular Stomach: Calcium Chloride.- Reversion of Transformed NIH 3T3 Cells to Flat Cells by Inhibitors of Poly(ADP-ribose) Polymerase.- Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin.- Establishment of a Highly Reproducible Transformation Assay of a Ras-Transfected Balb 3T3 Clone by Treatment with Promoters.- Antimutagenic Effect of umuD Mutant Plasmids: Isolation and Characterization of umuD Mutants reduced in their Ability to Promote UV Mutagenesis in Escherichia Coli.- Antitumor-promoting Activity of Sesquiterpene Isolated from an Herbal Spice.- Inhibitory Effects of Chlorogenic Acid, Reserpine, Polyprenoic ACID (E-5166), or Coffee on Hepatocarcinogenesis in Rats and Hamsters.- Antimutagenic Structure Modification of Quinoline: Fluorine-substitution at Position-3.- Mutagenicity and Antimutagenicity of Thai Medicinal Plants.- Influence of Potential Antioxidants on Free-radical Damage of Lymphocytes.- Specificity of Antimutagens Against Chemical Mutagens in Microbial Systems.- Classification of Mechanisms of Inhibitors of Mutagenesis and Carcinogenesis.- Antimutagenic Effects of Chlorophyllin.- Participants, Speakers, and Chairmen.