Part I. The Political Bioethics of Regulating Genetic Engineering: 1. Regulation Guided by Proceduralism; 2. Regulation Guided by Less-than-Universal Standards; 3. Regulation Guided by Human Nature as Construction Not Essence; 4. Regulation Guided by Human Dignity as Decisional Autonomy Not Essence; Part II. The Political Dimensions of Engineering Intelligence: 5. Threshold Capacities for Political Participation; 6. Political Capacity of Human Intelligence and the Challenge of AI; 7. Political Ambiguity of Personalized Education Informed by the Pupil's Genome; Part III. Inequality as Unintended Consequence Locally and as a Planetary Phenomenon: 8. A Human Right to Freedom from Genetic Disability; 9. Deploying Epigenetics to Identify Responsibility for Health Inequalities; 10. Genetic Engineering as a Technology of the Anthropocene; Coda: Bioethics as Political Theory.