Engineering of Human Tissues and Implants

ISBN-13: 9781032399027 / Twarda / 2024 / 240 str.

Robert Wood Johnson Medica Frederick H. (Dept. of Pathology

Opis

This text presents information on biological control systems, mechanotransduction, tissue structure and function and properties that can be integrated together to provide improved implant and device designs. This information is also needed to develop new diagnostic tests and instruments that provide early diagnostic results for diseases.

Spis treści

1. Introduction to Biomaterials and Biocompatibility  2. Structure and Properties of Biological Macromolecules  3. Physical Properties of Biological Macromolecules  4. Assembly of Macromolecules into Structural Elements  5. Introduction to Tissue Structure  6. Analysis of the Relationship Between Tissue Structure and Properties  7. Biological Cascades, the Biological Control Systems, and How they Influence Implant Design  8. Biomechanical Measurements on Soft Tissues  9. Introduction to Mechanotransduction  10. Pathobiology of Tissue Responses to Implants  11. Introduction to Tissue Engineering

O autorze

Dr. Frederick H. Silver is a Professor of Pathology and Laboratory Medicine and at Robert Wood Johnson Medical School, Rutgers, the State University of New Jersey. He did his Ph.D. in Polymer Science and Engineering at M.I.T. with Dr. Ioannis Yannas, the inventor of the Integra artificial skin, followed by a postdoctoral fellowship in Developmental Medicine at Mass General Hospital in Boston, MA with Dr. Robert L. Trelstad, a connective tissue pathologist. A US Patent has been granted and US and European patents are pending on vibrational evaluation of materials which he invented to provide a non-invasive “virtual biopsy” of tissues including skin cancers. His interests include the structure and properties of extracellular matrix in health and diseases and mechanobiology. Dr. Silver has published over 250 peer reviewed scientific papers and has over 20 patents issued and pending. He is a section editor in Biomaterials for the MDPI Journal Biomolecules.