New and Exploratory Therapeutic Agents for Asthma

ISBN-13: 9780824778613 / Angielski / Twarda / 1999 / 524 str.

Michael Yeadon; Zuzana Diamant

Opis

This work addresses treatment strategies for asthma, focusing on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. It presents information on the epidemiology, pathology, pharmacology and pulmonology of asthma, and discusses three major classes of asthma therapies - bronchodilators, anti-inflammatories and anti-allergics - as well as potential new therapeutic approaches.

Spis treści

Epidemiology of Asthma
Stephen T. Holgate and A. N. Banik
Pathophysiology of Asthma
Peter J. Sterk
Pathology of Asthma
Ratko Djukanoviâ
Muscarinic Receptor Subtypes and Anticholinergic Therapy
Allison D. Fryer, Richard W. Costello, and David B. Jacoby
Long-Acting 2-Agonist Drugs
Richard Beasley, Julian Crane, and Carl Burgess
Inhaled Glucocorticoids, Established and New
Joseph D. Spahn and Stanley J. Szefler
Platelet-Activating Factor Antagonists in Bronchial Asthma
Devendra K. Agrawal and Robert G. Townley
Tachykinin Receptor Antagonists
Guy F. Joos and Charles Advenier
Therapeutic Potential of Phosphodiesterase Type 4 Inhibitors in the Treatment of Asthma
Bernadette Hughes and Gerry Higgs
Leukotriene Modulators
Anthony P. Sampson and Zuzana Diamant
The Anti-IgE Treatment Strategy for Asthma
John V. Fahy
Activity of T-Cell Subsets in Allergic Asthma
André Boonstra and Huub F. J. Savelkoul
New Targets for Future Asthma Therapy
Peter J. Barnes
Current Practice and Future Trends in Clinical Trials in Asthma
Johan C. Kips and Romain A. Pauwels

O autorze

Yeadon, Michael; Diamant, Zuzana