Hormones, Gender and the Aging Brain: The Endocrine Basis of Geriatric Psychiatry

ISBN-13: 9780521653046 / Angielski / Twarda / 2000 / 378 str.

Mary F. Morrison (University of Pennsylvania)

Opis

The significance of hormone action in psychiatry has long been studied, but only recently has this study included the psychiatric effects of hormones on the aging process. Hormones influence a wide scope of states and conditions, ranging from pain tolerance and anorexia to attention, mood, immunity, cardiovascular and cognitive function, schizophrenia, and Alzheimer's disease. Written by an eminent team of psychiatrists, psychologists, geriatricians, and neuropharmacologists, this pioneering clinical reference addresses the hormonal basis of mental disorders in older people. This book brings together established information and recent findings in four sections:

An overview of the basic science of neurosteroids

Sex difference and the roles that cortisol, thyroid hormone, and the sex steroids estrogen, progesterone, dehydroepiandrosterone and testosterone play in common mental disorders and pain sensitivity

Psychoneuroimmunology in relation to age

Sex differences and hormones in psychotropic drug metabolism in the elderly.

Recenzje

'… clear, well presented … it offers plenty of ideas for future research in the area of endocrinology and psychiatry …' Bebe Fahy, International Journal of Geriatric Psychiatry

Spis treści

List of contributors; Preface; Acknowledgements; Part I. Overview: 1. Summary chapter. The endocrine basis of geriatric psychiatry: an integrative approach John E. Morley; 2. Overview of steroids in the aging brain Loretta M. Flanagan-Cato; Part II. Hormones and Mental Health in the Elderly: 3. The hypothalamic-pituitary-adrenal axis in aging: preclinical and clinical studies John W. Kasckow, Thomas D. Geracioti Jr, Marta Pisarska, Ajit Regmi, Dewleen G. Baker and James J. Mulchahey; 4. The hypothalamic-pituitary-thyroid axis Gabriel K. Tsuboyama; 5. Estrogen and depression in aging women Mary F. Morrison and Kathryn Tweedy; 6. The role of testosterone in male depression Stuart N. Seidman and Steven P. Roose; 7. Dehydroepiandrosterone in aging and mental health Owen M. Wolkowitz, Patricia D. Kroboth, Victor I. Reus and Tanya J. Fabian; 8. Sex hormones, cognition and dementia in the elderly Kristine Yaffe; 9. Effects of estrogen on basal forebrain cholinergic neurons and cognition: implications for brain aging and dementia in women Robert B. Gibbs; 10. Gender and schizophrenia Laurie A. Lindamer, M. Jackuelyn Harris, Julie Akiko Gladsjo, Robert Heaton, Jane S.Paulsen, Shelley C. Heaton and Dilip V. Jeste; 11. Sex steroids and anxiety disorders Teresa A. Pigott; 12. Gender and hormonal factors in pain and pain inhibition Wendy F. Sternberg; Part III. Effects of Hormones and Behavior on Immune Function: 13. Estrogens, stress and psychoneuroimmunology in women over the lifespan Mary H. Burleson, Susan Robinson-Whelan, Ronald Glaser and Janice K. Kiecolt-Glaser; 14. Gender differences in immune function at the cellular level Eva Redei and Suresh G. Shelat; Part IV. Hormones and Gender Differences in Psychotropic Drug Metabolism: 15. Gender differences in psychotropic drug metabolism Bruce G. Pollock; 16. The influence of progesterone on the pharmacokinetics and pharmacodynamics of gamma-aminobutyric acid-active drugs Patricia D. Kroboth and James W. McAuley; Index.