Pharmacognosy: Fundamentals, Applications and Strategies

ISBN-13: 9780443186578 / Angielski / Miękka / 2023

Simone Badal McCreath; Yuri N. Clement

Opis

Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

Spis treści

Section 1: Pharmacognosy 101 1. Background to pharmacognosy 2. Traditional medicine 3. Plant anatomy and physiology 4. Plant constituents: carbohydrates, oils, resins, balsams, and plant hormones 5. Plant crude drugs Section 2: Plant metabolites: their chemistry 6. Evolutionary perspectives on the role of plant secondary metabolites 7. Glycosides 8. Alkaloids 9. Tannins 10. Terpenoids 11. Other plant metabolites 12. Vitamins Section 3: Plant metabolites: their effects 13. Chemotherapeutics 14. Bioactive plant molecules, sources, and mechanisms of action in the treatment of cardiovascular diseases 15. Plant metabolites for treating diseases 16. Psychoactive drugs Section 4: Metabolites from other sources 17. Marine metabolites: oceans of opportunity 18. Animal metabolites: from amphibians, reptiles, Aves/birds, and invertebrates 19. Fungal metabolites: a focus on endophytes Section 5: Crude drugs from animals 20. Fats 21. Waxes Section 6: Basic animal anatomy and physiology 22. Basic animal anatomy and physiology 23. Proteins 24. Pharmacokinetics 25. Pharmacodynamics- a pharmacognosy perspective 26. Drug metabolism Section 7: Technological applications using biological systems 27. Biotechnology: principles and applications Section 8 Current trends in pharmacognosy research 28. Nuclear magnetic resonance spectroscopy in drug discovery 29. Metabolomics approach in pharmacognosy 30. Novel targets in drug discovery 31. Nanotechnology: creating, manipulating, and observing nanostructured systems in biology and medicine 32. Ethical aspects of working with local communities and their biological resources 33. Factors to consider in development of nutraceutical and dietary supplements 34. The global regulatory framework for medicinal plants