SECTION I: INTRODUCTION 1. Introduction to Concepts of Pathology 2. Epigenetics: Behavioral, Social, and Environmental Factors 3. Physiologic Self-Regulation: The Intersection with Mental, Social, and Emotional Well-Being 4. Environmental and Occupational Medicine 5. Problems Affecting Multiple Systems 6. Injury, Inflammation, Healing, and Repair SECTION II: CLINICAL MEDICINE 7. The Immune System 8. Infectious Disease 9. Oncology 10. The Integumentary System 11. The Endocrine and Metabolic Systems 12. The Cardiovascular System 13. The Lymphatic System 14. The Hematologic System 15. The Respiratory System 16. The Gastrointestinal System 17. The Hepatic, Pancreatic, and Biliary Systems 18. The Renal and Urologic Systems 19. The Male Genital/Reproductive System 20. The Female Genital/Reproductive System 21. Transplantation SECTION III: PATHOLOGY OF THE MUSCULOSKELETAL SYSTEM 22. Introduction to Pathology of the Musculoskeletal System 23. Genetic and Developmental Disorders 24. Metabolic Disorders 25. Infectious Diseases of the Musculoskeletal System 26. Musculoskeletal Neoplasms 27. Soft Tissue, Joint and Bone Disorders SECTION IV: PATHOLOGY OF THE NERVOUS SYSTEM 28. Introduction to Central Nervous System Disorders 29. Infectious Disorders of the Central Nervous System 30. Central Nervous System Neoplasms 31. Degenerative Diseases of the Central Nervous System 32. Stroke 33. Traumatic Brain Injury 34. Traumatic Spinal Cord Injury 35. Cerebral Palsy 36. Epilepsy 37. Headache 38. Vestibular Disorders 39. The Peripheral Nervous System SECTION V: IMPORTANT RESOURCES 40. Laboratory Tests and Values Appendix A: Guidelines for Activity and Exercise