Intestinal Lipid Metabolism

ISBN-13: 9780306462412 / Angielski / Twarda / 2000 / 434 str.

Charles M. Mansbach; Arnis Kuksis; Patrick Tso

Opis

This book was stimulated by the enthusiasm shown by attendees at the meetings in Saxon River, VT, sponsored by the Federation ofAmerican Societies for Experimental Biology (FASEB), on the subject of the intestinal processing of lipids. When these meetings were first started in 1990, the original organizers, two of whom are editors ofthis volume (CMM and PT), had two major goals. The first was to bring together a diverse group ofinvestiga tors who had the common goal of gaining a better understanding of how the intestine ab sorbs lipids. The second was to stimulate the interest of younger individuals whom we wished to recruit into what we believed was an exciting and fruitful area ofresearch. Since that time, the field has opened up considerably with new questions being asked and new an swers obtained, suggesting that our original goals for the meetings were being met. In the same spirit, it occurred to us that there has not been a recentbook that draws to gethermuch ofthe informationavailableconcerninghow the intestineprocesses lipids. This book is intended to reach investigators with an interest in this area and their pre- and post doctoral students. The chapters are written by individuals who have a long-term interest in the areas about which they write, and many have been speakers at the subsequent FASEB conferences that have followed on the first.

Spis treści

Preface. 1. Biophysics of intestinal luminal lipids; H.J. Verkade, P. Tso. 2. Preduodenal lipases and their role in lipid digestion; L. Dupuis, et al. 3. Molecular mechanisms of pancreatic lipase and co-lipase; M.E. Lowe. 4. Pancreatic lipase, physiological studies; H. Brockman. 5. Biology, pathology, and interfacial enzymology of pancreatic phospholipase A2; R. Homan, M.K. Jain. 6. Enterostatin/procolipase: A peptide system regulating fat intake; C. Erlanson-Albertsson. 7. Cholesterol esterase; P.N. Howles, D.Y. Hui. 8. The influence of the intestinal unstirred water layers on the understanding of the mechanisms of lipid absorption; A.B.R. Thomson, G. Wild. 9. The role of fatty acid-binding proteins in enterocyte fatty acid transport; J. Storch. 10. Microsomal triglyeride transfer protein: Role in the assembly of intestinal lipoproteins; J.R. Wetterau. 11. Intestinal synthesis of triacylglycerols; A. Kuksis, R. Lehner. 12. Triacylglycerol movement in enterocytes; C.M. Mansbach II. 13. Regulation of intestinal cholesterol metabolism; F.J. Field. 14. Regulation of intestinal apolipoprotein gene expression; D.D. Black. 15. Recent progess in the study of intestinal apolipoproteinB gene expression; N.O. Davidson, S. Anant. 16. The role of apolipoprotein A-IV as a satiety factor; P. Tso, T. Doi. 17. The possible role of intestinal surfactant-like particles in the absorption of triacylglycerols in the rat; D.H. Alpers, et al. 18. Inhibitors of chylomicron formation and secretion; J.B. Rodgers. 19. Intestinal absorption and metabolism of peroxidized liquids; T.S. LeGrand, T.Y. Aw. 20. Intestinal absorption of fat-soluble vitamins; M. Meydani, K.R. Martin. 21. Intestinal metabolism of intersterified fats; C.-E. Høy and H. Mu. 22. Structured triacylglycerols in clinical nutrition; S.J. DeMichele, B.R. Bistrian.