1. Introduction: The human hypothalamus and neuroendocrine disorders SECTION 15 Structural disorders of the hypothalamo-pituitary region 2. Pituitary stalk interruption syndrome 3. Empty sella syndrome: Multiple endocrine disorders 4. Pituitary dysfunction after aneurysmal subarachnoidal hemorrhage 5. Septo-optic dysplasia SECTION 16 Tumors of the hypothalamus 6. Hypothalamic hormone-producing tumors 7. Craniopharyngiomas primarily affecting the hypothalamus SECTION 17 Neuroimmunological disorders 8. The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects 9. Neuroendocrine manifestations of Langerhans cell histiocytosis 10. Neuroendocrine manifestations of Erdheim-Chester disease 11. Hypothalamitis and pituitary atrophy 12. Narcolepsy Type I as an autoimmune disorder 13. Neuromyelitis optica, aquaporin-4 antibodies, and neuroendocrine disorders 14. Antibodies against the pituitary and hypothalamus in boxers 15. Autoimmune diabetes insipidus SECTION 18 Drinking disorders 16. Neuroimaging of central diabetes insipidus 17. Differential diagnosis of familial diabetes insipidus 18. The vasopressin-aquaporin-2 pathway syndromes 19. Adipsic diabetes insipidus 20. Animal models for diabetes insipidus 21. Nocturnal enuresis in children: The role of arginine-vasopressin SECTION 19 Eating disorders 22. Monogenic human obesity syndromes 23. Hypothalamic microinflammation 24. Glucose and fat sensing in the human hypothalamus 25. Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling 26. Prader-Willi syndrome: Hormone therapies 27. Transcriptomics of the Prader-Willi syndrome hypothalamus 28. Disorders of hypothalamic function: Insights from Prader-Willi syndrome and the effects of craniopharyngioma 29. Animal models for Prader-Willi syndrome 30. Is there a hypothalamic basis for anorexia nervosa? SECTION 20 Reproduction, olfaction and sexual behavior 31. Sexual differentiation of the human hypothalamus: Relationship to gender identity and sexual orientation 32. Klinefelter syndrome or testicular dysgenesis: Genetics, endocrinology, and neuropsychology 33. Neurobiology of puberty and its disorders