Neural Regeneration

ISBN-13: 9780128017326 / Angielski / Twarda / 2015 / 444 str.

So, Kwok-Fai Xu, Xiao-Ming

Opis

Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including:

1. Neural regeneration in lower vertebrates
2. Neural regeneration in the peripheral nervous system
3. Neural regeneration in the central nervous system
4. Transplantation-mediated neural regeneration
5. Clinical and translational research on neural regeneration

The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research.

• Provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration
• Highly translational and clinically-relevance
• International authors who are leaders in their respective fields
• Vivid art work making the chapters easily understood

Spis treści

Section I.  Introduction Chapter 1. Advances and Challenges in Neural Regeneration Research Section II. Neural Regeneration in Lower Vertebrates Chapter 2. Functional Regeneration and Remyelination in the Zebrafish Optic Nerve Chapter 3. Central Nerve Regeneration in Reptiles Chapter 4. Axon Regeneration in the Lamprey Spinal Cord Section III. Neural Regeneration in the Peripheral Nervous System Chapter 5. Tissue engineering in Peripheral Nerve Regeneration Chapter 6. Brachial plexus avulsion: a model for axonal regeneration study Chapter 7. Conditions Affecting Accuracy of Peripheral Nerve Reinnervation and Functional Recovery Chapter 8. Gonadal Steroids in Regeneration and Repair of Neuromuscular Systems Section IV. Neural Regeneration in the CNS Chapter 9. Myelin-Associated Inhibitors in Axonal Growth After CNS Injury Chapter 10. The Nogo Receptor Pathway in CNS Regeneration and Therapeutic Opportunities Chapter 11. Astrogliosis and Axonal Regeneration Chapter 12. The Intrinsic Determinates of CNS Regeneration in the Central Nervous System Chapter 13. Optic Nerve Regeneration in Lower Vertebrates and Mammals: Bridging the Gap Chapter 14. Self-assembling Peptides Mediate Axonal Regeneration Chapter 15. Wnt Signaling in Spinal Cord Injury Chapter 16. Inflammation and secondary damage after spinal cord injury Chapter 17. Neuroprotection of Retinal Ganglion Cells in Glaucoma by Blocking LINGO-1 Function, or Using Nogo-66 Receptor Antagonist Chapter 18. Axonal Regeneration in the Dorsal Column Sensory Pathway Section V. Transplantation-Mediated Neural Regeneration Chapter 19. Peripheral Nerve Graft Mediated Axonal Regeneration Chapter 20. Olfactory ensheathing glial transplantation-mediated neural regeneration Chapter 21. Glial restricted precursor transplantation-mediated axonal regeneration Chapter 22. Schwann cell-mediated axonal regeneration in the CNS Chapter 23. Fetal Spinal Cord Transplantation and Axonal Regeneration: Around and Back Again Section VI. Clinical and Translational Research on Neural Regeneration Chapter 24. Spinal Cord Injury: Exercise and Clinical Trials Chapter 25. Spinal Cord Regeneration Chapter 26. Biomarkers for CNS Injury and Regeneration Chapter 27. High Content Screening Applied to Nervous System Injury: Advantages, Challenges, and Proof of Principle

O autorze

Prof Kwok-Fai So is the Director of GHM Institute of CNS Regeneration at Jinan University, Guangzhou, China; Chair of Anatomy in the State Key Laboratory of Brain and Cognitive Sciences, and the Department of Ophthalmology, Jessie Ho Professor in Neuroscience, The University of Hong Kong, member of the Chinese Academy of Sciences, member of the Advisory Committee, Ministry of Education/ 2011 Program, member of Biolgical and Medicine Council/ Ministry of Education, member of Consultative Committee/ the national 973 Program/ major national research funding program in China, Director of China Spinal Cord Injury Network (ChinaSCINet), Co-Chairman of the Board of Director of the ChinaSCINet, and Editor-in-Chief of Neural Regeneration Research.
He received PhD degree from MIT. He is one of the pioneers in the field of axonal regeneration in visual system. He was the first to show lengthy regeneration of retinal ganglion cells in adult mammals with peripheral nerve graft. He is currently using multiple approaches to promote axonal regeneration in the optic nerve and spinal cord. His team identifies neuroprotective and regenerative factors including: exercise, wolfberry, trophic factors, peptide nanofiber scaffold, and environmental manipulation. 1995 obtained the Natural Science Award of the National Natural Science Foundation of China. 1999 was elected Member of the Chinese Academy of Sciences. 2015 was elected US National Academy of Invention Fellow. 2017 elected a member of DABI (Dana Alliance for Brain Initiatives). He is the author and co-author of over 440+ publications and co-inventor of 28 patents. Scientific Director, Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute

Professor and Mari Hulman George Chair of Neurological Surgery

Professor, Department of Anatomy and Cell Biology

Indiana University, USA