β3 Adrenoreceptor

ISBN-13: 9780748408047 / Angielski / Twarda / 2000 / 188 str.

A. D. Strosberg

Opis

The Beta-3 Adrenoreceptor plays an important role in regulating human fat storage and variants of this receptor are thought to be relevant to diabetes.
In addition to the major interest in obesity and diabetes expressed by the pharmaceutical industry, increasing numbers of academic groups are attracted by this general research area. This renewed interest is of course in part stimulated by available financing from industry. It also reflects the growing realisation that metabolism remains an open frontier: little is known about adipocyte sub-populations, specific markers, or endocrine functions. Research on the 3 adrenoreceptor and discussion about the hypothetical 4 adrenoreceptor is currently stimulating considerable interest which will certainly be satisfied by this volume. The Beta-3 Adrenoreceptor will appeal to readers at graduate and post-graduate levels of all major universities and other research and education institutes.

Spis treści

Introduction - Structure and Function of the ß3-Adrenoreceptor. Regulation of the ß3-Adrenoreceptor Signalling Efficacy. Using Transgenic and Gene Knockout Techniques to Assess ß3-Adrenoreceptor Function. ß3-Adrenoreceptor Ligands and the Pharmacology of ß3-Adrenoreceptor. The Native Human ß3-Adrenoreceptor. ß3-Adrenoreceptor-Mediated Responses in Heart and Vessels. ß3-Adrenoreceptors in Brown and White Adipocytes: Roles in Thermogenesis and Energy Balance. The Putative "ß4"-Adrenoreceptor and Other Atypical ß-Adrenoreceptors.

O autorze

A. Donny Strosberg