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Cancer is a class of diseases in which a group of cells display uncontrolled growth, invasion, and sometimes metastasis.. Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing. However, there are cases of aggressive prostate cancers. The cancer cells may metastasize from the prostate to other parts of the body, particularly the bones and lymph nodes. Loss of PTEN and concomitant activation of AKT could act in partnership with the TMPRSS2-ERG fusion protein to promote progression to prostate cancer...

HIV is a member of the genus Lentivirus, part of the family of Retroviridae. Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the most common and pathogenic strain of the virus. Despite the success of highly active antiretroviral therapy (HAART) in controlling HIV infection and reducing HIV associated mortality, current drug regimens are unable to completely eradicate HIV infection. Bioinformatics methods based on complex networks and Gene Ontologies (GOs) come to our rescue in predicting the possible targets for such diseases and are very useful in this area. This work...