Lipid Signaling in Plants
ISBN: 9783642038723 / Angielski / Twarda / 330 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Phospholipidshavelongbeenknownfortheirkeyroleinmaintainingthebilayer structureofmembranesandinphysicallyseparatingthecytosolfromorganelles andtheextracellularspace. Inthepastdecade, acompletelynovelandunexpected functionemerged, full?llingacrucialroleincellsignaling. Itwasthediscoveryin animalcells, thatagonist-activatedcellsurfacereceptorsledtotheactivationofa phospholipase C (PLC), to hydrolyze the minor lipid, phosphatidylinositol 4- bisphosphateintotwosecondmessengers, inositol1,4,5-trisphosphate(InsP)and 3 2+ diacylglycerol(DAG). WhileInsP diffusesintothecytosol, whereitreleasesCa 3 2+...
Phospholipidshavelongbeenknownfortheirkeyroleinmaintainingthebilayer structureofmembranesandinphysicallyseparatingthecytosolfromorganelles andtheextra...
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582,32 zł |
New Methods for the Study of Biomolecular Complexes
ISBN: 9780792350033 / Angielski / Twarda / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A NATO Advanced Research Workshop entitled New Methods for the Study of Molecular Aggregates was held at Tbe Lodge at Kananaskis Village, Alberta, Canada from 16 -20 June 1996. In fact the meeting was entirely concerned with the problem of analyzing biomolecular complexes, so the title of these proceedings has been altered to give a more precise description of the content. Tbe workshop was hosted by the time-of-flight group of the Department of Physics at the University of Manitoba, and was attended by 64 participants from around the world. ' venty-one invited talks were given and 27 papers...
A NATO Advanced Research Workshop entitled New Methods for the Study of Molecular Aggregates was held at Tbe Lodge at Kananaskis Village, Alberta, Can...
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582,32 zł |
Glycotechnology
ISBN: 9780792386407 / Angielski / Twarda / 100 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Glycotechnology brings together in one place important contributions and up-to-date research results in this fast moving area.
Glycotechnology serves as an excellent reference, providing insight into some of the most challenging research issues in the field. Glycotechnology brings together in one place important contributions and up-to-date research results in this fast moving area.
Glyc... |
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582,32 zł |
Protein Trafficking in Plant Cells
ISBN: 9780792352372 / Angielski / Twarda / 343 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The highly structured eucaryotic cell with its complex division of biochemical labour requires a distinct protein complement in each cellular structure and compartment. Nuclear coded and cytosolically synthesized polypeptides are specifically sorted to every corner of the cell in a post- or co-translational manner. The presence of separate genomes and protein translation machineries in plastids and mitochondria requires further coordination not only on the transcriptional, translational but also most likely on the protein import level. Numerous different protein transport systems have...
The highly structured eucaryotic cell with its complex division of biochemical labour requires a distinct protein complement in each cellular structur...
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582,32 zł |
Methods in Non-Aqueous Enzymology
ISBN: 9783764358037 / Angielski / Twarda / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Extending the range of enzymatic catalysis by using non-aqueous media considerably enlarges the range of enzyme applications and became a po werful approach in biochemistry and biotechnology. This book discusses several specific applications in nearly anhydrous media, aqueous-orga nic co-solvent mixtures and reverse micelles, including use of enzymes in fat and oil processing, peptide synthesis, sugar transformations a nd preparation of chiral compounds. A particularly promising approach of using reverse micelles for modifying proteins is also described.
Extending the range of enzymatic catalysis by using non-aqueous media considerably enlarges the range of enzyme applications and became a po werful ap...
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582,32 zł |
5-Ht4 Receptors in the Brain and Periphery
ISBN: 9783540641643 / Angielski / Twarda / 229 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function. With chapters written by specialists in the field, this is a comprehensive review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors.
The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function. With chapters written by specialists in the field, this is a comp...
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582,32 zł |
Computational Methods for Macromolecules: Challenges and Applications: Proceedings of the 3rd International Workshop on Algorithms for Macromolecular
ISBN: 9783540437567 / Angielski / Miękka / 504 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 3 The workshop on Methods for Macromolecular Modeling (M ), held at New York University on 12- 14 October 2000, attracted 187 participants from Eu rope, Asia, the Americas, and the Middle East. (see monod.biomath .nyu.eduj rvhganjconfOO.html for more information). The exciting program was made possible by the dedicated work of the international advisory committee whose members were P. Deuflhard, J. Hermans, B. Leimkuhler, A. E. Mark, S. Reich, T. Schlick, and R. Skeel. We are indebted to the following agen cies and institutions for their generous support: the Burroughs Wellcome Fund,...
3 The workshop on Methods for Macromolecular Modeling (M ), held at New York University on 12- 14 October 2000, attracted 187 participants from Eu rop...
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582,32 zł |
Insulin Action
ISBN: 9780792381136 / Angielski / Twarda / 194 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II...
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume...
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582,32 zł |
Chromosome Painting: Principles, Strategies and Scope
ISBN: 9780792370093 / Angielski / Twarda / 179 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Chromosome Painting is the most modern and novel technique for directly identifying several gene sequences simultaneously in the chromosome, with the aid of specific probes in molecular hybridization. Its resolution ranges from single copy to entire genome sequences. It is now applied in plant, animal, and human systems, in gene mapping, identification of genetic disorders, evolutionary studies, and gene transfer experiments. This treatise is the first of its kind to cover the technique with all its modifications and applications. It is designed for regular use by postgraduate students and...
Chromosome Painting is the most modern and novel technique for directly identifying several gene sequences simultaneously in the chromosome, with the ...
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582,32 zł |
Molecular Chaperones
ISBN: 9780412550607 / Angielski / Twarda / 121 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview chapters discuss the significance of chaperones in biochemistry, molecular genetics and cell biology. Each chapter is well referenced providing access to the literature.
Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key fig...
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582,32 zł |
Base Excision Repair of DNA Damage
ISBN: 9780412131615 / Angielski / Twarda / 188 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover uracil DNA glycosylases, repair of oxidized purines in DNA, mammalian mismatch-specific DNA glycosylases, repair of apurinic/apyrimidic sites in DNA by AP endonucleases, mutagenesis of abasic sites, a pro
Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover urac...
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582,32 zł |
Frontiers in Bioactive Lipids
ISBN: 9780306455056 / Angielski / Twarda / 313 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent advances in our understanding of the fundamental role of bioactive lipids in normal and abnormal physiology was the theme of the XVlth International Spring Sympo 6-9, 1996 at the George Washington University School sium on Health Sciences held on May of Medicine in Washington, D.C. Over 250 participants shared their latest findings on fundamental mechanisms in lipid metabolism, transport, and signal transduction. Most of the papers presented at the plenary sessions have been collected in this volume, which is divided into seven parts. The focus of Part I is on the new roles that fatty...
Recent advances in our understanding of the fundamental role of bioactive lipids in normal and abnormal physiology was the theme of the XVlth Internat...
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582,32 zł |
Forkhead Transcription Factors: Vital Elements in Biology and Medicine
ISBN: 9781441915986 / Angielski / Twarda / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders. Equally important, Forkhead Transcription Factors: Vital... Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insigh... |
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582,32 zł |
Discovering Life, Manufacturing Life: How the experimental method shaped life sciences
ISBN: 9789048137664 / Angielski / Twarda / 418 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Francis BACON, in his Novum Organum, Robert BOYLE, in his Skeptical Chemist and Rene DESCARTES, in his Discourse on Method; all of these men were witnesses to the th scientific revolution, which, in the 17 century, began to awaken the western world from a long sleep. In each of these works, the author emphasizes the role of the experimental method in exploring the laws of Nature, that is to say, the way in which an experiment is designed, implemented according to tried and tested te- niques, and used as a basis for drawing conclusions that are based only on results, with their margins of...
Francis BACON, in his Novum Organum, Robert BOYLE, in his Skeptical Chemist and Rene DESCARTES, in his Discourse on Method; all of these men were witn...
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582,32 zł |
Understanding Insulin Action: Principles and Molecular Mechanisms
ISBN: 9780412022616 / Angielski / Twarda / 129 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Every year between three and four hundred papers are published on the topic of insulin action. This extraordinary publication rate prevents any author from includ- ing an exhaustive bibliography in any review or book. Perhaps due to this there is no single text that attempts to cover the effects and the mechanism of action of insulin. This book is such an attempt. I intend to present a review of the physiological effects of insulin, the pathology of defects in the action of insulin, and the current views on the mechanism of action of this hormone. I make no apology for the fact that the...
Every year between three and four hundred papers are published on the topic of insulin action. This extraordinary publication rate prevents any author...
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582,32 zł |
Basic Protein and Peptide Protocols
ISBN: 9780896032682 / Angielski / Twarda / 490 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first volume in this Methods Molecular Biology series, Proteins (1984), concentrated on basic techniques for the analysis and purification of peptides and proteins. As the series developed, more specialized volumes on proteins were introduced, such as those on Immunochemical Protocols (vol. 10), Practical Protein Chro- tography (vol. 11), Analysis Glycoprotein Biomedicine (vol. 14), Protein-DNA Interactions (vol. 30), Biomembrane Protocols (vols. 19 and 27), Analyses and Methods (vol. 17), and Optical Spectroscopy, Microscopy, and Macroscopic Techniques (vol. 22). Further specialist...
The first volume in this Methods Molecular Biology series, Proteins (1984), concentrated on basic techniques for the analysis and purification of pept...
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582,32 zł |
Galanin
ISBN: 9783034602273 / Angielski / Twarda / 286 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This overview of galanin research shows how the identification, isolation and characterization of this peptide was brought about and how its functionality was revealed as the pharmacological tools to dissect galaninergic mechanisms were developed.
This overview of galanin research shows how the identification, isolation and characterization of this peptide was brought about and how its functiona...
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582,32 zł |
Multiscale Approaches to Protein Modeling
ISBN: 9781441968883 / Angielski / Twarda / 355 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dynamics, folding mechanisms and macromolecular interactions. It approaches span a wide range of the levels of coarse-grained representations, various sampling techniques and variety of applications to biomedical and biophysical problems. This book is intended to be used as a reference book for those who are just beginning their adventure with biomacromolecular modeling but also as a valuable source of detailed information for those who are... The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dy... |
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582,32 zł |
Small Molecule Microarrays: Methods and Protocols
ISBN: 9781607618447 / Angielski / Twarda / 242 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries,...
Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a...
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582,32 zł |
MIPS and Their Roles in the Exchange of Metalloids
ISBN: 9781441963147 / Angielski / Twarda / 145 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subsequent years of research showed that the water channel AQP1 was only the tip of an iceberg; the iceberg itself being the ubiquitous super family of membrane intrinsic proteins (MIPs) that facilitate trans-membrane transport of water and an increasing number of small, water-soluble and uncharged compounds. Here we introduce you to the superfamily of MIPs and provide a summary about our gradually refined understanding of the phylogenetic relationship...
Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subseque...
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582,32 zł |