NMR of Proteins and Small Biomolecules
ISBN: 9783642429040 / Angielski / Miękka / 248 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Application of NMR and Molecular Docking in Structure-Based Drug Discovery, by Jaime L. Stark and Robert Powers NMR as a Unique Tool in Assessment and Complex Determination of Weak Protein-Protein Interactions, by Olga Vinogradova and Jun Qin The Use of Residual Dipolar Coupling in Studying Proteins by NMR, by Kang Chen und Nico Tjandra NMR Studies of Metalloproteins, by Hongyan Li and Hongzhe Sun Recent Developments in 15N NMR Relaxation Studies that Probe Protein Backbone Dynamics, by Rieko Ishima Contemporary Methods in Structure Determination of Membrane Proteins by Solution NMR, by...
Application of NMR and Molecular Docking in Structure-Based Drug Discovery, by Jaime L. Stark and Robert Powers NMR as a Unique Tool in Assessment and...
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781,79 zł |
Regulatory RNAs: Basics, Methods and Applications
ISBN: 9783642442841 / Angielski / Miękka / 554 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also increasingly clear that these play... Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discoverin... |
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781,79 zł |
Mass Spectrometry in Metabolomics: Methods and Protocols
ISBN: 9781493912575 / Angielski / Twarda / 360 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and... Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomic... |
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781,79 zł |
Comparative Physiology of Fasting, Starvation, and Food Limitation
ISBN: 9783642447303 / Angielski / Miękka / 430 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. All animals face the possibility of food limitation and ultimately starvation-induced mortality. This book summarizes state of the art of starvation biology from the ecological causes of food limitation to the physiological and evolutionary consequences of prolonged fasting. It is written for an audience with an understanding of general principles in animal physiology, yet offers a level of analysis and interpretation that will engage seasoned scientists. Each chapter is written by active researchers in the field of comparative physiology and draws on the primary literature of starvation both...
All animals face the possibility of food limitation and ultimately starvation-induced mortality. This book summarizes state of the art of starvation b...
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781,79 zł |
RNA Metabolism in Trypanosomes
ISBN: 9783642433252 / Angielski / Miękka / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most...
Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sick...
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781,79 zł |
Cell Biology of Extracellular Matrix: Second Edition
ISBN: 9781461366805 / Angielski / Miękka / 468 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor- mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won- dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We...
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has ...
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781,79 zł |
Non-Fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases
ISBN: 9789400798953 / Angielski / Miękka / 568 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Amyloid-forming proteins are implicated in over 30 human diseases. The proteins involved in each disease have unrelated sequences and dissimilar native structures, but they all undergo conformational alterations to form fibrillar polymers. The fibrillar assemblies accumulate progressively into disease-specific lesions in vivo. Substantial evidence suggests these lesions are the end state of aberrant protein folding whereas the actual disease-causing culprits likely are soluble, non-fibrillar assemblies preceding the aggregates. The non-fibrillar protein assemblies range from small, low-order...
Amyloid-forming proteins are implicated in over 30 human diseases. The proteins involved in each disease have unrelated sequences and dissimilar nativ...
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781,79 zł |
Interplay Between Metal Ions and Nucleic Acids
ISBN: 9789401782944 / Angielski / Miękka / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base...
Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationall...
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781,79 zł |
Nucleic Acid Drugs
ISBN: 9783642437410 / Angielski / Miękka / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. New Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, by Mariana Kiomy Osako, Hironori Nakagami und Ryuichi Morishita Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides, by Ekambar R. Kandimalla und Sudhir Agrawal Delivery of Nucleic Acid Drugs, by Yan Lee und Kazunori Kataoka Aptamer: Biology to Applications, by Yoshikazu Nakamura Development and Clinical Applications of Nucleic Acid Therapeutics, by Veenu...
New Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynuc...
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781,79 zł |
Enzyme-Catalyzed Electron and Radical Transfer
ISBN: 9781475782219 / Angielski / Miękka / 693 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Dramatic advances have been made in recent years in the field of redox enzymology which has resulted in an increase of research activities. This volume will cover the recent milestone developments in this field by leading experts, uniting theory and experiment, and selecting contributions to illustrate important aspects of the mechanisms of electron and radical transfer in proteins.
Features:
Dramatic advances have been made in recent years in the field of redox enzymology which has resulted in an increase of research activities. This volum...
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781,79 zł |
Bacterial Growth and Lysis: Metabolism and Structure of the Bacterial Sacculus
ISBN: 9781475793611 / Angielski / Miękka / 474 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume is based on a FEMS Symposium entitled "Bacterial Growth and Lysis: Metabolism and Structure of the Bacterial Sacculus" held at the Monastery of Lluc (Mallorca, Spain) on 5-10 April, 1992. The goals of the symposium were to assess the present state of knowledge on the structure and physiology of the bacterial murein sacculus, and to develop new hypotheses and strategies to promote further development of the field. Consequently, the contributions compiled in this volume include broadly different approaches, from the introduction of new analytical methods to the presentation of...
This volume is based on a FEMS Symposium entitled "Bacterial Growth and Lysis: Metabolism and Structure of the Bacterial Sacculus" held at the Monaste...
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781,79 zł |
The Biology of Acinetobacter: Taxonomy, Clinical Importance, Molecular Biology, Physiology, Industrial Relevance
ISBN: 9781489935557 / Angielski / Miękka / 452 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 1st International Workshop on Acinetobacter was held on 6th September, 1986, in Manchester, England, in association with the 14th International Congress of Microbiology. That occasion was so well attended and productive that there were soon discussions about how, when and where the next meeting should be held. This time, however, there was sufficient confidence to think of a more substantial meeting and to plan for the proceedings to be published. It emerged that there was wide agreement that the time was ripe to take stock of the entire biology of Acinetobacter: its occurrence and...
The 1st International Workshop on Acinetobacter was held on 6th September, 1986, in Manchester, England, in association with the 14th International Co...
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781,79 zł |
Water and Ions in Biological Systems
ISBN: 9781489904263 / Angielski / Miękka / 824 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As the First International Conference on Water and Ions in Biological Systems (Bucharest, June 25-27, 1980) was appreciated as a success, a second one was organized in the fall of the year 1982 under the sponsorship of the United Nations Educational, Scientific and Cultural Organization (UNESCO), the Romanian Academy of Medical Sciences, the Romanian Biophysical Society (Union of Societies for Medical Sciences in the Socialist Republic of Romania) and in co operation with the International Union for Pure and Applied Bio physics (IUPAB). The responsibility for the scientific program and...
As the First International Conference on Water and Ions in Biological Systems (Bucharest, June 25-27, 1980) was appreciated as a success, a second one...
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781,79 zł |
Class 2 Transferases III: EC 2.3.1.60 - 2.3.3.15
ISBN: 9783642436277 / Angielski / Miękka / 698 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement... The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized and here is the second, updated editio... |
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781,79 zł |
Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid Beta
ISBN: 9781461498414 / Angielski / Miękka / 409 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, biochemical, immunological and structural studies. It is these latter that receive attention within this book. This compilation of 20 chapters indicates the diversity of work currently in progress and summarizes the current state of knowledge. Experienced authors who are scientifically active in their fields of study have been selected as contributors to this book, in an attempt to present a reasonably complete survey of the field. Inevitably,...
To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, ...
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781,79 zł |
Nf-Kappa B: Methods and Protocols
ISBN: 9781493924219 / Angielski / Twarda / 668 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Focusing on essential insight into the methods and techniques required to dissect the complex mechanisms of NF-κB activation, regulation, and function. NF-kappa B: Methods and Protocols guides readers through standard approaches to detect NF-κB pathway activation, detection and analysis of NF-κB signaling, and methods to study the control of NF-κB signaling. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily... Focusing on essential insight into the methods and techniques required to dissect the complex mechanisms of NF-κB activation, regulation, and ... |
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Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design
ISBN: 9781489996114 / Angielski / Miękka / 323 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London WC1E 7H United Kingdom Email: g. waksman@bbk. ac. uk and g. waksman@ucl. ac. uk Phone: (+44) (0) 207 631 6833 Fax: (+44) (0) 207 631 6833 URL: http: //people. cryst. bbk. ac. uk/?ubcg54a Gabriel Waksman is Professor of Structural Molecular Biology at the Institute of Structural Molecular Biology at...
Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Addre...
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781,79 zł |
Class 2 Transferases II: EC 2.1.2.1 - 2.3.1.59
ISBN: 9783642426667 / Angielski / Miękka / 725 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement... The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized and here is the second, updated editio... |
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781,79 zł |
Ecto-Nox Proteins: Growth, Cancer, and Aging
ISBN: 9781489988454 / Angielski / Miękka / 508 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.
This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX p...
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781,79 zł |
Proteomic Profiling: Methods and Protocols
ISBN: 9781493925490 / Angielski / Twarda / 501 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents the latest developments of the main pillars of protein analysis, such as sample preparation, separation and characterization. The book begins by describing basic but important sample preparation protocols. It then goes on to describe more sophisticated procedures on enriching specific protein classes and concludes with detailed descriptions of integrated work-flows for comprehensive protein analysis and characterization. The authors of the individual chapters are renowned protein biochemists who have all set value to provide a detailed representation of their lab work.... This volume presents the latest developments of the main pillars of protein analysis, such as sample preparation, separation and characterization. ... |
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781,79 zł |