In Vitro Toxicity Testing Protocols
ISBN: 9781489940827 / Angielski / Miękka / 332 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In vitro toxicology is one of the most rapidly expanding areas of biological research today. It is generally conceded that this is a result of pressure from the public for safer products and environmental conditions and, in these recessionary times, pressure from company accountants, who often perceive in vitro experimentation as a cheaper option than lawsuits, fines, and expensive remediation. Toxicologists themselves form one group whose vigor and influence on the evolution of in vitro toxicology is often underestimated. Many toxicologists have for some time been unhappy with the quantity...
In vitro toxicology is one of the most rapidly expanding areas of biological research today. It is generally conceded that this is a result of pressur...
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cena:
389,09 zł |
Metal Carcinogenesis Testing: Principles and in Vitro Methods
ISBN: 9781489940919 / Angielski / Miękka / 169 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical descriptions of rapid and inexpensive in vitro assay methodology presently in use for the detection of potentially carci- nogenic metals and their compounds. Mounting experimental evidence has suggested that a number of metals and their compounds are potentially carcinogenic to humans. Since humans are exposed to these potentially carcinogenic metals in industrial situations and through environmental pollution, it is essential that experimental...
Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical...
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389,09 zł |
Drugs Between Research and Regulations: Proceedings of the 5th International Meeting of Pharmaceutical Physicians Munich, October 14-17, 1984
ISBN: 9783642541322 / Angielski / Miękka / 206 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Franz Gross died suddenly during preparations for the meeting. He would have taken great pleasure in summarizing in this preface the aims and results of a gathering which so clearly bore his imprint as Chairman of the Scientific Program Committee. His sudden passing away is deeply regretted by all of us: organizers, speakers and participants. We greatly respect him for his exceptional abilities, his impact on science and his qualities as a human being. He provided the impulse for a well balanced and topical scientific program. We therefore dedicate the proceedings of this symposium to his...
Franz Gross died suddenly during preparations for the meeting. He would have taken great pleasure in summarizing in this preface the aims and results ...
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389,09 zł |
Antimalarial Drugs I: Biological Background, Experimental Methods, and Drug Resistance
ISBN: 9783662349915 / Angielski / Miękka / 486 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,09 zł |
Antibiotics: Volume I Mechanism of Action
ISBN: 9783662376492 / Angielski / Miękka / 785 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,09 zł |
Metronomic Chemotherapy: Pharmacology and Clinical Applications
ISBN: 9783662436035 / Angielski / Twarda / 295 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology...
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has ...
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cena:
389,09 zł |
Metabonomics and Gut Microbiota in Nutrition and Disease
ISBN: 9781447165385 / Angielski / Twarda / 375 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of... This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health c... |
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389,09 zł |
Technical Aspects of Toxicological Immunohistochemistry: System Specific Biomarkers
ISBN: 9781493915156 / Angielski / Twarda / 231 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special...
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquat...
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cena:
389,09 zł |
Introduction to Drug Metabolism
ISBN: 9780412263903 / Angielski / Miękka / 293 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Although the scientific literature on drug metabolism is extensive, it suffers from the disadvantage that the material is diffuse and consists largely of specialist monographs dealing with particular aspects of the subject. In addi tion, although there are a few excellent texts on drug metabolism in print, these tend to be earlier publications and hence do not take into account the many recent advances in this area. Our motivations for writing this book therefore arose from the clear need for a recent and cohesive introductory text on this subject, specifically designed to cater for the needs...
Although the scientific literature on drug metabolism is extensive, it suffers from the disadvantage that the material is diffuse and consists largely...
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389,09 zł |
Pharmacokinetics: A Modern View
ISBN: 9781461297253 / Angielski / Miękka / 548 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,09 zł |
Methods in Pharmacology
ISBN: 9781461574279 / Angielski / Miękka / 585 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The death of Sir Henry Hallett Dale two years ago brought to a close an era which was characterized by tremendous pharmacologic advancements. During this period, the employment of what present investigators might consider "primitive" techniques yielded information which has become classic. For example, in a paper by Barger and Dale, published in 1910*, one finds not only a beautiful example of a structure-activity study and suggestions of the importance of membranes, but also the concept of specific receptor sites introduced by the statement that "the relation of the receptive mechanism to...
The death of Sir Henry Hallett Dale two years ago brought to a close an era which was characterized by tremendous pharmacologic advancements. During t...
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cena:
389,09 zł |
Biomedical Applications of Immobilized Enzymes and Proteins: Volume 2
ISBN: 9781468426151 / Angielski / Miękka / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,09 zł |
Pharmacology of Antibiotics
ISBN: 9781468431254 / Angielski / Miękka / 436 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen- icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer...
The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meetin...
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cena:
389,09 zł |
Biological Reactive Intermediates--II: Chemical Mechanisms and Biological Effects
ISBN: 9781475706765 / Angielski / Miękka / 846 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,09 zł |
Sucralfate: From Basic Science to the Bedside
ISBN: 9781475770193 / Angielski / Miękka / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.
International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease the...
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389,09 zł |
Drug Policy and Human Nature: Psychological Perspectives on the Prevention, Management, and Treatment of Illicit Drug Abuse
ISBN: 9781489935939 / Angielski / Miękka / 326 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The formation of drug policy is a complex phenomena influenced by a multi- tude of sources. Among others, these influences include historical factors, contemporary public opinion regarding the nature and magnitude of drug use and abuse, the portrayal of illicit drugs and drug use in the media, and lobbying efforts by special interest groups (e. g., The Drug Policy Foundation), including government agencies (e. g., the Justice Department and law enforcement). An additional source of influence are the activities of specialists directly engaged in studying drug use and treating drug dependence....
The formation of drug policy is a complex phenomena influenced by a multi- tude of sources. Among others, these influences include historical factors,...
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cena:
389,09 zł |
Cardiac Drug Development Guide
ISBN: 9781489938282 / Angielski / Miękka / 431 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and molecular aspects of therapeutic drug development. The chapters comprise a broad spectrum of therapeutic areas and hence involve a comprehensive discussion of molecular, biochemical, and electrophy- ological concepts based on years of in vitro as well as in vivo pharmacological st- ies. In addition, the...
Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and deve...
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cena:
389,09 zł |
Drug Targeting: Strategies, Principles, and Applications
ISBN: 9781489941718 / Angielski / Miękka / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Advances in understanding the molecular mechanisms of disease together with the advent of recombinant DNA and other technologies have opened opportunities for a vast array of novel therapeutic biopharmaceuticals and diagnostic agents. However, even natural biomolecules present a myriad of problems that limit their potential as pharmaceutical agents. Rapid degra- tion and elimination, immunological reactions, and toxicity are often asso- ated with new biopharmaceuticals, much as with conventional agents. Targeted delivery systems have the potential to increase the efficacy of existing...
Advances in understanding the molecular mechanisms of disease together with the advent of recombinant DNA and other technologies have opened opportuni...
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cena:
389,09 zł |
Protocols in in Vitro Hepatocyte Research
ISBN: 9781493920730 / Angielski / Twarda / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents 30 state-of-the-art protocols and reviews to set up and apply primary hepatocyte cultures for research and screening purposes. The first part of the book focuses on the use of these particular liver-based in vitro models to study the different aspects of the hepatocyte life cycle, including cell growth, differentiation and cell death. The second part of the book is targeted towards the demonstration of the applicability of primary hepatocyte cultures, or liver-based in vitro models derived thereof, for functionality and toxicity testing. Written in the... This volume presents 30 state-of-the-art protocols and reviews to set up and apply primary hepatocyte cultures for research and screening purposes.... |
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389,09 zł |
Inflammatory Disorders
ISBN: 9783319100111 / Angielski / Twarda / 67 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of...
The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-...
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cena:
389,09 zł |