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The Alkaloids: Chemistry and Biology
ISBN: 9780124695603 / Angielski / Twarda / 414 str. Termin realizacji zamówienia: ok. 22 dni roboczych. This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, T...
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948,05 zł |
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Macrolide Antibiotics: Chemistry, Biology, and Practice
ISBN: 9780125264518 / Angielski / Twarda / 635 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their functio...
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676,90 zł |
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Intermediate Filament Cytoskeleton
ISBN: 9780125641739 / Angielski / Twarda / 855 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Intermediate filaments are a large family of proteins that are the cytoskeletal elements involved in a number of skin, liver, neuromuscular, cardiac, eye and hair diseases. Intermediate filament genes are regulated in a tissue-and cell type-specific manner and their polymerized protein products protects the cells and tissue they are part of against a variety of mechanical and nonmechanical stresses. This book provides a comprehensive resource of methodology essentials, describing a variety of essential tools and assays for studying intermediate filaments. The book provides user-friendly...
Intermediate filaments are a large family of proteins that are the cytoskeletal elements involved in a number of skin, liver, neuromuscular, cardiac, ...
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643,70 zł |
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Diuretic Agents: Clinical Physiology and Pharmacology
ISBN: 9780126356908 / Angielski / Twarda / 666 str. Termin realizacji zamówienia: ok. 22 dni roboczych. The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines.
The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as ...
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671,37 zł |
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Biochemistry of Redox Reactions
ISBN: 9780126853919 / Angielski / Twarda / 471 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative, up-to-date text includes the following features, unavailable elsewhere: First in a set of books to provide a comprehensive coverage of drug metabolism; Opening chapter provides a general introduction to the complete set of books; Other chapters cover reaction mechanisms, catalytic cycles, regio- and stereoselectivities, types of substrates, reactivity of intermediates, and drug-enzyme interactions; Extensive detailed diagrams of reaction pathways and chemical...
Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative, up-to-date text inc...
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948,05 zł |
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Vitamins and Hormones
ISBN: 9780127098661 / Angielski / Twarda / 611 str. Termin realizacji zamówienia: ok. 22 dni roboczych. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists,...
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the ...
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809,71 zł |
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Controlled Drug Release of Oral Dosage Forms
ISBN: 9780131749542 / Angielski / Twarda / 410 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. This book provides clear and straightforward information enabling the reader to carry out numerical analysis of matter transfer - a vital processs when looking at the formulation of oral dosage forms with controlled drug release. The drug is dispersed in a polymeric matrix (either biodegradable or not), the basis of which is the transfer of the liquid and the drug through dosage form. Information on this...
Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled dru...
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1446,68 zł |
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An Account of the Foxglove and Its Medical Uses 1785-1985
ISBN: 9780192615015 / Angielski / Twarda / 350 str. Termin realizacji zamówienia: ok. 24 dni roboczych. This unique two-part discussion of foxglove--the herb from which digitalis is derived--features a facsimile of William Withering's classic "An Account of Foxglove and Some of its Medical Uses," complete with explanatory notes interpreting this eighteenth century text for the modern reader. The second part of the book, written by J.K. Aronson, co-author of the Oxford Textbook of Clinical Pharmacology, includes an introduction to the botany and pharmacology of foxgloves, their therapeutic uses before Withering, a short biography of Withering, an account of 18th century medical practices, and...
This unique two-part discussion of foxglove--the herb from which digitalis is derived--features a facsimile of William Withering's classic "An Account...
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1541,59 zł |
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Medicinal Chemistry: A Molecular and Biochemical Approach
ISBN: 9780195104561 / Angielski / Miękka / 649 str. Termin realizacji zamówienia: ok. 12-16 dni roboczych. Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and biochemical principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles,...
Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive,...
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464,49 zł |
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Pharmacology of Cytokines
ISBN: 9780198500421 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 24 dni roboczych. This book overviews the field of cytokine research and describes the v arious approaches that have been taken to develop the pharmacology of these novel mediators. The pharmacology of cytokines is an exploding a rea which is entering the clinical arena. The book in the framework of the immunobiology of cytokines, examines the interactions with the cy tokine system of a variety of compounds ranging from simple synthetic chemicals to biotechnological products. In addition to examining indiv idual agents and approaches, the book examines the pathophysiology of individual body systems and...
This book overviews the field of cytokine research and describes the v arious approaches that have been taken to develop the pharmacology of these nov...
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1385,03 zł |
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Antibody Engineering: A Practical Approach
ISBN: 9780199635924 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 24 dni roboczych. Recombinant DNA techniques have revolutionized the isolation and production of antibodies in recent years. This has resulted in rapid changes in how to handle antibodies for research. This new Practical Approach volume responds to this change by assembling, in one volume, protocols which allow the researcher to isolate a new antibody, analyse its properties, format the right antibody molecule or fragment, and produce it in usable quantities. The book is divided into two parts: the first describes the generation and analysis of antibodies and the second covers engineering and production. This...
Recombinant DNA techniques have revolutionized the isolation and production of antibodies in recent years. This has resulted in rapid changes in how t...
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cena:
884,06 zł |
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Integration of Pharmaceutical Discovery and Development: Case Histories
ISBN: 9780306457432 / Angielski / Twarda / 610 str. Termin realizacji zamówienia: ok. 18 dni roboczych. In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g., high affinity and specificity for the target receptor), pharmaceutical (e....
In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented...
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1365,58 zł |
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Calcium Channel Pharmacology
ISBN: 9780306478789 / Angielski / Twarda / 418 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Voltage-gated calcium channels are critical regulators of cytoplasmic levels of calcium, the universal signaling ion. As such, calcium channels trigger a wide range of cellular functions, from muscle contraction to neurotransmitter secretion, and are important players in human disease. Prominent in the nervous, cardiovascular, and endocrine systems, members of the calcium channel family are targets for existing antihypertensive and anticonvulsant drugs. In addition, they are emerging targets for drugs to treat an extraordinarily diverse group of disorders, including pain, cerebral ischemia,...
Voltage-gated calcium channels are critical regulators of cytoplasmic levels of calcium, the universal signaling ion. As such, calcium channels trigge...
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cena:
977,50 zł |
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Antibodies: Vol 1 + 2
ISBN: 9780306483349 / Angielski / Twarda / 550 str. Termin realizacji zamówienia: ok. 18 dni roboczych. If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including:
-concepts in development of manufacturing strategies, If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations m...
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cena:
899,93 zł |
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Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
ISBN: 9780387233840 / Angielski / Twarda / 395 str. Termin realizacji zamówienia: ok. 18 dni roboczych. As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic... As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as... |
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831,97 zł |
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Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications
ISBN: 9780415263658 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource.
For the first time, Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications presents state-of-the-art information on various cytotoxins and immunotoxins in a single, highly anticipated publication. The editors bring together leading researchers to summarize... Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Alth...
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cena:
921,00 zł |
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Biology of Marijuana: From Gene to Behavior
ISBN: 9780415273480 / Angielski / Twarda / 660 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Marijuana is the prototypical cannabinoid and is one of the most widely used drugs in the world. Cannabinoids are molecules found naturally in the human body and brain as well as in cannabis.
Marijuana is the prototypical cannabinoid and is one of the most widely used drugs in the world. Cannabinoids are molecules found naturally in the hum...
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cena:
1026,13 zł |
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Proteinase and Peptidase Inhibition
ISBN: 9780415273497 / Angielski / Twarda / 440 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest over recent decades. At present, specific protease inhibitors are exploited both as tools in unraveling the role of individual proteinases in particular cellular processes and for the development of chemotherapeutic agents for the treatment of various disorders. Proteinase and Peptidase Inhibition presents updated progress reports on the characterization of a wide range of cellular proteinases whose inhibitors may hold the key to the development of new drugs. Introductory...
Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest over recent decades. At present...
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cena:
1052,42 zł |
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Molecular Pathomechanisms and New Trends in Drug Research
ISBN: 9780415277259 / Angielski / Twarda / 664 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Knowledge of the basic mechanisms of human disease is essential for any student or professional engaged in drug research and development. Functional gene analysis (genomics), protein analysis (proteomics), and other molecular biological techniques have made it possible to understand these cellular processes, opening up exciting opportunities for novel therapeutic possibilities.
Molecular Pathomechanisms and New Trends in Drug Research presents an in-depth review of the molecular mechanisms involved in a number of common diseases including cancer, AIDS, inflammation, cardiovascular disease... Knowledge of the basic mechanisms of human disease is essential for any student or professional engaged in drug research and development. Functional g...
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cena:
947,28 zł |
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Pharmaceutical Perspectives of Nucleic Acid-Based Therapy
ISBN: 9780415283854 / Angielski / Twarda / 568 str. Termin realizacji zamówienia: ok. 18 dni roboczych. Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by...
Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a compre...
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cena:
1052,42 zł |
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