Cancer and Energy Balance, Epidemiology and Overview
ISBN: 9781461425939 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is the first book in the book series, Energy Balance and Cancer, so the series editor will be organizing it himself. This is the first book in the book series, Energy Balance and Cancer, so the series editor will be organizing it himself. |
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781,79 zł |
New Trends in Cancer for the 21st Century
ISBN: 9789048172399 / Angielski / Miękka / 396 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians,... It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives.... |
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781,79 zł |
Mammary Tumorigenesis and Malignant Progression: Advances in Cellular and Molecular Biology of Breast Cancer
ISBN: 9781461361091 / Angielski / Miękka / 361 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth...
The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer....
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781,79 zł |
Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development: Proceedings of the Twenty-Second Annual Cancer Symposium Detroit,
ISBN: 9781461365488 / Angielski / Miękka / 409 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The focus of the 22nd Annual Detroit Cancer Symposium was the presentation and discussion of cytotoxic agents, with a significant portion of the symposium including the exciting frontiers of drug discovery being explored by the National Cooperative Drug Discovery Groups (NCDDG) Program. The symposium brought together a large number of investigators from government, universities and pharmaceutical companies involved in the discovery and development of new anticancer agents. Exciting new leads were presented and the status of others presently under development was discussed.
Of particular... The focus of the 22nd Annual Detroit Cancer Symposium was the presentation and discussion of cytotoxic agents, with a significant portion of the sympo...
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781,79 zł |
Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment
ISBN: 9781461367383 / Angielski / Miękka / 173 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative, but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology tex...
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781,79 zł |
Advances in Lymphoma Research
ISBN: 9781461368519 / Angielski / Miękka / 169 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Fernando Cabanillas In 1993, Fisher et al. published the results of a randomized trial comparing three third-generation regimens against the classic CHOP combination. For several years, the oncology community had been convinced that the third generation regimens were clearly superior to CHOP. It came as a shock to many that there was no difference in outcome between the four arms of this clinical trial. The logical conclusion is that CHOP is as good as any of the other regimens tested in that study. Unfortunately, this excellent study has been misinterpreted by many as proving that there has...
Fernando Cabanillas In 1993, Fisher et al. published the results of a randomized trial comparing three third-generation regimens against the classic C...
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781,79 zł |
Enzyme-Prodrug Strategies for Cancer Therapy
ISBN: 9781461371861 / Angielski / Miękka / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours.
This book is the first to describe ADEPT in detail. Each chapter reviews an aspect of the immunology, enzymology, biochemistry, chemistry, and cancer... Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody deliver...
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781,79 zł |
Phosphoinositide 3-Kinase in Health and Disease: Volume 2
ISBN: 9783642265303 / Angielski / Miękka / 306 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost invariably encounter roadblocks, often exposing unresolved questions in the basic understanding of the target
PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impa...
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781,79 zł |
Trends in Stem Cell Proliferation and Cancer Research
ISBN: 9789400762107 / Angielski / Twarda / 661 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.
The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiologic...
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781,79 zł |
Mechanisms of Oncogenesis: An Update on Tumorigenesis
ISBN: 9789400732117 / Angielski / Miękka / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Thisvolumeisacontinuationoftheencyclopedicworkentitled CancerGrowthand Progression, thatwasoriginallyeditedbyProfessorHansE. Kaiser. Asatributeto thememoryofDr. Kaiserandhiscontributionstothe eld, thisneweditionisf- lowinghisexampleofprovidingthemostcurrentinformationaboutcancerliterature andcomprehensivecoverageofallaspectsoftumorgrowthandprogression. Thisparticulartomeisdividedintotwosections: the rstaddressinggeneralcauses ofoncogenesissuchasenvironmentalfactorsandtumormechanisms;andthesecond addressingtheoncogenicmechanismsoftumorinspeci corgans. Thisbookiswr-...
Thisvolumeisacontinuationoftheencyclopedicworkentitled CancerGrowthand Progression, thatwasoriginallyeditedbyProfessorHansE. Kaiser. Asatributeto them...
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781,79 zł |
Pediatric Cancer, Volume 4: Diagnosis, Therapy, and Prognosis
ISBN: 9789400765900 / Angielski / Twarda / 346 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This entry in the series Pediatric Cancer offers comprehensive information on a variety of cancers, concentrating on brain tumors, the most common solid tumors and the leading cause of cancer- related mortality in children. The contents are organized in seven sections: Neuroblastoma, Medulloblastoma, Leukemia, Lymphoma, Rhabdoid, Sarcoma and Miscellaneous Tumors. Coverage includes pediatric medulloblastoma, and treatments including craniospinal radiation followed by adjuvant chemotherapy. The contributors explain diagnosis and chemotherapy of children with acute lymphoblastic leukemia, and...
This entry in the series Pediatric Cancer offers comprehensive information on a variety of cancers, concentrating on brain tumors, the most common sol...
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781,79 zł |
Brain Tumor Invasiveness
ISBN: 9781461361244 / Angielski / Miękka / 82 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is widely appreciated that the pathophysiology of advanced brain cancer is intimately related to the extent of tumor invasiveness. A prerequisite for comprehensively understanding neuro-oncology is therefore the elucidation of the biochemical and molecular properties of tumor cells that contribute to their invasiveness. An understanding of tumor invasion for central nervous system tumors is crucial since malignant brain tumors are very highly invasive and extensively destroy adjacent neural brain tissue. Moreover, they are angiogenesis-dependent and lead to the death of patients by...
It is widely appreciated that the pathophysiology of advanced brain cancer is intimately related to the extent of tumor invasiveness. A prerequisite f...
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781,79 zł |
Prognostic Variables in Node-Negative and Node-Positive Breast Cancer
ISBN: 9781461373667 / Angielski / Miękka / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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781,79 zł |
The Tumor Microenvironment
ISBN: 9781461426608 / Angielski / Miękka / 770 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment...
The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial ce...
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781,79 zł |
Molecular Genetics of Liver Neoplasia
ISBN: 9781461427315 / Angielski / Miękka / 399 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Primary liver cancer is the third most deadly and fifth most common cancer worldwide ( 500,000 deaths annually), with a sharp increase of incidence in the United States in recent years. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major types of primary liver cancer. Risk factors include gender, hepatitis B virus (HBV), hepatitis C virus (HCV), cirrhosis, metabolism diseases, diabetes, obesity, toxins, excess alcohol consumption and smoking. Liver cancer arises most frequently in inflammatory livers with extensive oxidative stress due to viral hepatitis which causes... Primary liver cancer is the third most deadly and fifth most common cancer worldwide ( 500,000 deaths annually), with a sharp increase of incidence... |
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781,79 zł |
Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases
ISBN: 9783642368264 / Angielski / Twarda / 339 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during...
There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neur...
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781,79 zł |
Metastasis of Colorectal Cancer
ISBN: 9789400732933 / Angielski / Miękka / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally... Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-relat... |
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781,79 zł |
Chronic and Acute Leukemias in Adults
ISBN: 9781461296195 / Angielski / Miękka / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general on- cology textbooks are generally out of date. Single papers in specialized jour- nals are informative but seldom comprehensive; these are more often pre- liminary reports on a very limited number of patients. Certain general jour- nals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev- er...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general on- cology t...
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cena:
781,79 zł |
Multidisciplinary Treatment of Soft Tissue Sarcomas
ISBN: 9781461363460 / Angielski / Miękka / 191 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The previous volume of this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, the focus of which is continued in the present edition. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology techniques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of the prognosis of the patient as well as providing data for the planning of treatment strategy. The use of cytogenetics is relatively new in this field. This...
The previous volume of this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, the focus of whi...
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781,79 zł |
Molecular and Clinical Advances in Anticancer Drug Resistance
ISBN: 9781461367260 / Angielski / Miękka / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The importance of drug resistance in cancer chemotherapy cannot be over- stated. The 500,000 patients who die every year from cancer in the United States have, in most cases, been treated with chemotherapy. Many of these patients responded initially to chemotherapy, but death resulted from the development of drug-resistant tumors. In the first volume in the series. Drug Resistance in Chemotherapy the results of comprehensive laboratory studies aimed at understanding the mechanisms for resistance to individual agents and to the development of broad cross-resistance were described. In the past...
The importance of drug resistance in cancer chemotherapy cannot be over- stated. The 500,000 patients who die every year from cancer in the United Sta...
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781,79 zł |