Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development
ISBN: 9783642451973 / Angielski / Twarda / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never cause a problem again. In this book we will therefore make a journey from asking how more...
To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evo...
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583,65 zł |
Glioma Cell Biology
ISBN: 9783709114308 / Angielski / Twarda / 468 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gliomas are fatal diseases, but also represent good models for tumor research with the aim to eventually discover new and appropriate therapeutics against this disease. Glioma experimental research models are of help to investigate tumorigenesis (tumor stem cell theory versus -classical- opinions), tumor angiogenesis (since they are highly vascularized) and tumor invasion (since they grow without limits). In addition, they have a very special microenvironment (the brain) and limited tumor stroma cells (mainly microglia and endothelial cells). This book addresses the molecular mechanisms of...
Gliomas are fatal diseases, but also represent good models for tumor research with the aim to eventually discover new and appropriate therapeutics aga...
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cena:
583,65 zł |
Energy Balance and Hematologic Malignancies
ISBN: 9781489994219 / Angielski / Miękka / 186 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution....
The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hemat...
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583,65 zł |
Management of Castration Resistant Prostate Cancer
ISBN: 9781493911752 / Angielski / Twarda / 337 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in depth review of proven therapeutic options, including bone targeted therapies, immunotherapy, chemotherapy and hormonal based therapies. Combination therapy as well as novel targeted approaches presently under investigations are also reviewed. The text provides up to date guidelines and algorithms for the management of CRPC based on international guidelines presently available as well as evidence based medicine. As... This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. ... |
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583,65 zł |
Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring: An Introduction
ISBN: 9789401791670 / Angielski / Twarda / 471 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up.In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are... DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid fro... |
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583,65 zł |
Retroviruses and Insights Into Cancer
ISBN: 9781489981431 / Angielski / Miękka / 363 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease. This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an ... |
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583,65 zł |
Gynecologic Oncology: A Pocketbook
ISBN: 9781493919758 / Angielski / Miękka / 427 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During this age of advanced technology, there is an incredible amount of dynamic literature surrounding the diagnosis and treatment of gynecologic cancers. Despite this information surplus, house officers and junior faculty studying gynecologic oncology indicate a need for a reliable, easily accessible, streamlined resource for everyday use. Gynecologic Oncology: A Pocketbook is a collaborative effort that combines the perspectives of expert faculty and fellows in training in the field of gynecologic oncology. Not only is it incredibly portable, but the format in which the information...
During this age of advanced technology, there is an incredible amount of dynamic literature surrounding the diagnosis and treatment of gynecologic can...
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cena:
583,65 zł |
Health Services for Cancer Survivors: Practice, Policy and Research
ISBN: 9781489993472 / Angielski / Miękka / 395 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Health has been conceptualized by world and national health organizations (WHO, CDC, Healthy People 2010) as more than the absence of disease. It involves a focus on physical, psychosocial, and functional aspects of life as well as the prevention of future illnesses. At this point in the development of quality health care for cancer survivors, there is sufficient knowledge and expert opinion to push efforts forward to improve the health of cancer survivors. Clearly there is more research in the most prevalent forms of cancers (e.g., breast cancer) than others that provide us with guidance... Health has been conceptualized by world and national health organizations (WHO, CDC, Healthy People 2010) as more than the absence of disease. It i... |
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583,65 zł |
Cellular Respiration and Carcinogenesis
ISBN: 9781627039413 / Angielski / Miękka / 195 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanism or pathways of cellular respiration; oxidative phosphorylation and... Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the ... |
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583,65 zł |
Modern Clinical Trial Analysis
ISBN: 9781489987785 / Angielski / Miękka / 254 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume covers classic as well as cutting-edge topics on the analysis of clinical trial data in biomedical and psychosocial research and discusses each topic in an expository and user-friendly fashion. The intent of the book is to provide an overview of the primary statistical and data analytic issues associated with each of the selected topics, followed by a discussion of approaches for tackling such issues and available software packages for carrying out analyses. While classic topics such as survival data analysis, analysis of diagnostic test data and assessment of measurement... This volume covers classic as well as cutting-edge topics on the analysis of clinical trial data in biomedical and psychosocial research and discus... |
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583,65 zł |
Telomere Territory and Cancer
ISBN: 9789400795471 / Angielski / Miękka / 204 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Timing, racing, combating, struggling and targetingare some actions through which cellular fate could be reflected and evaluated. Interaction between cell territory and environment occur during pre-embryonic, fetal development, and post-natal periods. What the researchers observe as the outcome of telomeres behavior is only the peak of an ice mountain within a stormy ocean. Cellular life depends on programmed behavior of telomeres, capable to surprise the cells. Telomeres provide an introduction to the history of our cells which govern the quality of life and status of health. Telomeres as...
Timing, racing, combating, struggling and targetingare some actions through which cellular fate could be reflected and evaluated. Interaction between ...
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cena:
583,65 zł |
Morphofunctional Aspects of Tumor Microcirculation
ISBN: 9789401782043 / Angielski / Miękka / 116 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like normal blood vessels, they consist of endothelial cells, mural cells and their enveloping basement membrane. Common features, irrespective of their origin, size and growth pattern, are absent hierarchy, formation of large-caliber sinusoidal vessels, markedly heterogeneous density, increased...
Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and ...
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583,65 zł |
An Omics Perspective on Cancer Research
ISBN: 9789400790636 / Angielski / Miękka / 269 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving... Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (incl... |
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583,65 zł |
Progress in Colorectal Surgery
ISBN: 9781447156710 / Angielski / Miękka / 299 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Progress in Colorectal Surgery covers a variety of topics of current interest to the colorectal specialist. Thirteen areas are covered by internationally renowned experts and include chapters on topics such as referral guidelines for rectal bleeding, difficult intra-operative problems in pelvic surgery, advances in the medical treatment of Crohn's disease, adjuvant treatment for colorectal malignancy, thorough overview of modern developments in the surgical treatment of disorders of the lower intestine including ulcerative colitis/severe acute colitis and innovations in... Progress in Colorectal Surgery covers a variety of topics of current interest to the colorectal specialist. Thirteen areas are cov... |
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583,65 zł |
Hedgehog-Gli Signaling in Human Disease
ISBN: 9781489989765 / Angielski / Miękka / 228 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in... Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of r... |
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583,65 zł |
Desmoid Tumors
ISBN: 9789400793033 / Angielski / Miękka / 221 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Desmoid Tumors (DT), also called Aggressive Fibromatoses, are a rare fibroblastic proliferative disease, with an incidence of 2 to 4 new cases per million people per year. Despite the absence of a metastatic potential, DT cause significant morbidity and at times mortality due to its locally invasive behaviour. The anatomical locations can be abdominal, extra-abdominal (often in the extremities) and intra-abdominal. This book is the first manuscript dedicated entirely to Desmoid Tumors. Written by prominent clinicians, researchers and advocacy group experts, patients and professionals alike...
Desmoid Tumors (DT), also called Aggressive Fibromatoses, are a rare fibroblastic proliferative disease, with an incidence of 2 to 4 new cases per mil...
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cena:
583,65 zł |
Intensity-Modulated Radiation Therapy: Clinical Evidence and Techniques
ISBN: 9784431554851 / Angielski / Twarda / 473 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This...
Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliv...
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cena:
583,65 zł |
Proteins of the Nucleolus: Regulation, Translocation, & Biomedical Functions
ISBN: 9789400797185 / Angielski / Miękka / 371 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer....
This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure...
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cena:
583,65 zł |
Laparoscopic Surgery for Colorectal Cancer
ISBN: 9784431557104 / Angielski / Twarda / 238 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides simplified principles of surgical anatomy for colorectal cancers with sophisticated drawings, standard laparoscopic procedures with striking photographs and illustrations, and advanced procedures such as lateral pelvic node dissection and down to top or reverse total mesorectal excision. Oncological safety as well as minimum invasiveness of laparoscopic surgery for colorectal cancer has been acknowledged worldwide, based on long-term outcomes of several randomized controlled trials comparing laparoscopic surgery and open surgery. Developments in optical devices... This book provides simplified principles of surgical anatomy for colorectal cancers with sophisticated drawings, standard laparoscopic procedures w... |
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583,65 zł |
Cancer Chemoprevention and Treatment by Diet Therapy
ISBN: 9789401784672 / Angielski / Miękka / 316 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book examines the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. Coverage includes flavonoids from fruits and vegetables, flax seed oil, green tea, soy, and antioxidant-rich foods.
This book examines the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. Coverage includes flavo...
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cena:
583,65 zł |