P53 in the Clinics
ISBN: 9781461436751 / Angielski / Twarda / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This project follows on the success of the book "25 years of p53," published by Springer in 2006. Since this publication, there have been considerable advances on the potential application of p53 into the clinics. The goal of this book is to capture these developments and to appeal to a clinical and medical audience beyond the one which was the primary target of "25 years of p53."
This project follows on the success of the book "25 years of p53," published by Springer in 2006. Since this publication, there have been considerable...
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583,65 zł |
The Evolution of the Use of Mathematics in Cancer Research
ISBN: 9781461423966 / Angielski / Twarda / 404 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book will provide an exhaustive and clear explanation of how Statistics, Mathematics and Informatics have been used in cancer research, and seeks to help cancer researchers in achieving their objectives. To do so, state-of-the-art Biostatistics, Biomathematics and Bioinformatics methods will be described and discussed in detail through illustrative and capital examples taken from cancer research work already published. The book will provide a guide for cancer researchers in using Statistics, Mathematics and Informatics, clarifying the contribution of these logical sciences to the study of...
The book will provide an exhaustive and clear explanation of how Statistics, Mathematics and Informatics have been used in cancer research, and seeks ...
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cena:
583,65 zł |
Liver-Directed Therapy for Primary and Metastatic Liver Tumors
ISBN: 9781475733730 / Angielski / Miękka / 322 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and...
Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique mu...
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583,65 zł |
Checkpoint Controls and Targets in Cancer Therapy
ISBN: 9781617796357 / Angielski / Miękka / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which may manifest through either a failure to activate the checkpoint or a failure to respond to the activated checkpoint. In normal cells, checkpoint pathways are activated when genetic or cellular homeostasis is compromised, and signals are then... Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular prolifera... |
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583,65 zł |
Lipid a in Cancer Therapy
ISBN: 9781461424970 / Angielski / Miękka / 152 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cancer remains a major challenge for modern society. Not only does cancer rank among the first three causes of mortality in most population groups but also the therapeutic options available for most tumor types are limited. The existing ones have limited efficacy, lack specificity and their administration carry major side effects. Hence the urgent need for novel cancer therapies. One of the most promising avenues in research is the use of specific immunotherapy. The notion that the immune system may have important anti-tumor effects has been around for more than a century now. Every... Cancer remains a major challenge for modern society. Not only does cancer rank among the first three causes of mortality in most population groups ... |
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583,65 zł |
Pocket Guide to Ocular Oncology and Pathology
ISBN: 9783642289118 / Angielski / Twarda / 433 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This handbook is designed to serve as a compact, up-to-date, and easy-to-use reference on the clinical features and pathology of ocular tumors. It comprises approximately 75 entries that cover the full spectrum of clinically encountered ocular tumors as well as tumor classification and other selected topics. Each entry addressing a given tumor or class of tumors is organized in a standard way, with information on synonyms, definition, etiology, clinical presentation, diagnosis, differential diagnosis, prophylaxis, therapy, prognosis, and epidemiology. Key references are also provided. The... This handbook is designed to serve as a compact, up-to-date, and easy-to-use reference on the clinical features and pathology of ocular tumors. It ... |
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583,65 zł |
Renal Cell Carcinoma: Clinical Management
ISBN: 9781627030618 / Angielski / Twarda / 362 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the... Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable reso... |
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583,65 zł |
Energy Balance and Gastrointestinal Cancer
ISBN: 9781461423669 / Angielski / Twarda / 184 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and colon are each associated with obesity. This unique association is covered in this volume of "Energy Balance and Cancer" from the epidemiologic, biologic and potential etiologic viewpoint. The focus on possible dietary contribution as well as the role of exercise in prevention and therapy is presented in both animal model and patient based studies. Special focus is provided also on the role of genetic mutations and inflammatory pathways as...
The gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and c...
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cena:
583,65 zł |
Epigenetic Alterations in Oncogenesis
ISBN: 9781441999665 / Angielski / Twarda / 348 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means "above" genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in...
The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally mean...
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583,65 zł |
Systems Biology of Tumor Dormancy
ISBN: 9781461414445 / Angielski / Twarda / 294 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first annual CCSB workshop brought together biologists, mathematicians, and computer scientists to discuss various aspects of tumor dormancy and develop novel mathematical/computational models with the keynote speakers. This title is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011.
The first annual CCSB workshop brought together biologists, mathematicians, and computer scientists to discuss various aspects of tumor dormancy and d...
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cena:
583,65 zł |
Exercise, Energy Balance, and Cancer
ISBN: 9781461444923 / Angielski / Twarda / 242 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. While it is well established that the worldwide pandemic of overweight and obesity has profound effects on promoting cancer, it is now recognized that an alternative aspect of energy balance, namely physical activity and exercise have significant beneficial effects on all aspects of cancer across the spectrum from prevention through treatment and extending through survivorship. Moreover, salutary effects of physical activity and exercise extend across the age span from youth to old age and occur at all stages of cancer extending into palliative care. While the effect of...
While it is well established that the worldwide pandemic of overweight and obesity has profound effects on promoting cancer, it is now ...
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cena:
583,65 zł |
Advances in Biology and Therapy of Multiple Myeloma: Volume 1: Basic Science
ISBN: 9781461446651 / Angielski / Twarda / 322 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. Two major advances are making this goal possible. First, recent advances in genomics and proteomics in MM have allowed for...
Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance ...
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cena:
583,65 zł |
Cancer Immunotherapy: Paradigms, Practice and Promise
ISBN: 9781461447313 / Angielski / Twarda / 486 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This work offers a historical perspective on tumor immunotherapy, discusses fundamental mechanisms of failed tumor rejection, looks at passive strategies to boost anti-tumor immunity, and details active strategies to boost anti-tumor immunity.
This work offers a historical perspective on tumor immunotherapy, discusses fundamental mechanisms of failed tumor rejection, looks at passive strateg...
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cena:
583,65 zł |
DNA Repair of Cancer Stem Cells
ISBN: 9789400745896 / Angielski / Twarda / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The existence of cancer stem cells (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA...
The existence of cancer stem cells (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuou...
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583,65 zł |
Novel Apoptotic Regulators in Carcinogenesis
ISBN: 9789400749160 / Angielski / Twarda / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, established leaders in the field of apoptosis describe a number of novel apoptotic regulators -- both naturally occurring and chemically synthesized -- that have shown promising value and as well as great feasibility for cancer treatment.
In this book, established leaders in the field of apoptosis describe a number of novel apoptotic regulators -- both naturally occurring and chemically...
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cena:
583,65 zł |
Electric Cell-Substrate Impedance Sensing and Cancer Metastasis
ISBN: 9789400749269 / Angielski / Twarda / 260 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book reviews the fundamentals of electric cell-substrate impedance sensing, and recent progress which permits high-throughput automated analyses. Coverage focuses on applications in cell based investigations, particularly in the area of cancer biology.
This book reviews the fundamentals of electric cell-substrate impedance sensing, and recent progress which permits high-throughput automated analyses....
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cena:
583,65 zł |
Razoxane and Dexrazoxane - Two Multifunctional Agents: Experimental and Clinical Results
ISBN: 9789401780483 / Angielski / Miękka / 243 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines....
Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so tha...
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cena:
583,65 zł |
Role of the Transcriptome in Breast Cancer Prevention
ISBN: 9781461448839 / Angielski / Twarda / 454 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book will provide the latest advances in molecular and cellular biology for establishing the foundation of a complete understanding of the mechanisms of breast differentiation leading to cancer prevention. The authors are based on the epidemiological evidence indicating that early first full term pregnancy is a protective factor in human against breast cancer and they have used this paradigm and developed experimental systems in both in vivo and in vitro that have demonstrated mechanistically how the differentiation at the organ and cellular level takes place. This knowledge has provided...
This book will provide the latest advances in molecular and cellular biology for establishing the foundation of a complete understanding of the mechan...
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cena:
583,65 zł |
Leukemia and Related Disorders: Integrated Treatment Approaches
ISBN: 9781607615644 / Angielski / Twarda / 382 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From the world renowned Fred Hutchinson Cancer Research Center, this book is written for all physicians who treat patients with acute or chronic leukemias or myelodysplasia. It is designed to answer questions about treatment approaches that commonly arise in day-to-day practice. In keeping with the Center's groundbreaking research in bone marrow transplantation, the book provides exceptional coverage of the role of allogeneic transplant in treatment. It also addresses the important issues of supportive care and long-term complications of successful treatment. Edited and written by... From the world renowned Fred Hutchinson Cancer Research Center, this book is written for all physicians who treat patients with acute or chronic le... |
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583,65 zł |
Burkitt's Lymphoma
ISBN: 9781461443124 / Angielski / Twarda / 332 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The study of Burkitt's lymphoma is now in its 6 decade beginning with its discovery by Dr. Dennis Burkitt in equatorial Africa in the mid to late 1950's. A large body of information is available which provides a current understanding of the underlying molecular changes that are linked to the initiation and development of Burkitt's lymphoma. This proposed volume will provide a comprehensive view of Burkitt's Lymphoma from the diagnosis to potential animal models for this disease and include a view from physicians who have a up close view of the patients in populations where the disease is...
The study of Burkitt's lymphoma is now in its 6 decade beginning with its discovery by Dr. Dennis Burkitt in equatorial Africa in the mid to late 1950...
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cena:
583,65 zł |