Kategoria BISAC: Medical >> Immunology

This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity....

This book is about recurring celiac disease, its diagnosis and management. It starts by discussing the pathogenesis of refractory celiac disease and the role of viruses, microbiota and genetics in this disease. It also covers the epidemiological aspects.

Refractory Celiac Disease is a unique resource on the topic written by a team of international experts in the topic and will be of great use to gastroenterologists and researchers in the field.

This book provides a comprehensive overview of the biology of the endoplasmic reticulum (ER) and the associated ER proteins, it discusses their structure, function and signaling mechanisms in the cell and their role in disease. This book also offers insights into the practical aspects of research and demonstrates the use of non-mammalian models to study the structure and function of the ER. Written by leading experts in the field, the book enables readers to gain a thorough understanding of current ER biology. It is intended for scientists and clinical researchers working on the...

This book discusses the potential roles of miRNA as a crucial regulator in cancer biology. It examines the regulation of drug resistance by miRNAs in cancers and the mechanism of their deregulated expression. The book discusses the role and molecular mechanism of miRNA in regulating cellular proliferation and cell cycle. It analyses circulating miRNAs as biomarkers for cancer diagnosis and prognosis. It also analyzes the role of miRNA as a modulator of the development and function of tumor-associated immune cells. It explores the cross-talk between miRNA and reactive oxygen species (ROS)...

This book addresses the most relevant imaging techniques in order to detect inflammation and infection in the most common cardiovascular diseases. The book presents data concerning molecular imaging (SPECT and PET) and cardiac magnetic resonance imaging (MRI) for each disease, with a special focus on the emerging role of hybrid PET/MR imaging. Different non-ischemic and ischemic diseases as well as cardiac infections are addressed in detail; these include: Cardiac sarcoidosis, Cardiac amyloidosis, the vulnerable plaque, Post-infarction inflammatory alterations, Pericarditis, Myocarditis,...

This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets. Key features include discussion of mechanisms recently identified to be involved in the resolution phase of inflammation, presentation of the latest evidence regarding the roles of endogenous TLR4 ligands in metastasis, and thorough explanation of the concept of homeostatic inflammation and current understanding of the significance...