"Up to this year I have always felt that I had no particular call to meddle with this subject....But I feel now that the time is come when even a woman or a child who can speak a word for freedom and humanity is bound to speak." Thus did Harriet Beecher Stowe announce her decision to begin work on what would become one of the most influential novels ever written. The subject she had hesitated to "meddle with" was slavery, and the novel, of course, was Uncle Tom's Cabin. Still debated today for its portrayal of African Americans and its unresolved place in the literary canon, Stowe's...