A drug molecule has to be water soluble to be readily delivered to the cellular membrane but needs to be hydrophobic to cross the membrane. Delivering drugs in water-insoluble formulation is thus a critical matter in therapeutic drug development. This book serves as a comprehensive reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. Reflecting the significant progress and advances since the last edition, this edition revises and updates all of the chapters.
A drug molecule has to be water soluble to be readily delivered to the cellular membrane but needs to be hydrophobic to cross the membrane. Deliver...