a)Introduction to the problem: Maheshwari proposed the concept of mixed solvency. He is of the opinion that all substances whether liquids, gases or solids possess solubilizing power and hence concentrated aqueous solutions containing various dissolved substances can improve the solubility of poorly soluble drugs. Till now this concept have been utilized extensively in the field of pharmaceutical analysis and formulation development with an aim to preclude the use of organic solvent, avoids the problem of residual solvent toxicity, replace toxic class-II solvent by safer class-III solvent,...
a)Introduction to the problem: Maheshwari proposed the concept of mixed solvency. He is of the opinion that all substances whether liquids, gases or s...