The M-current (of the KCNQ2/3 channel) is voltage-
gated potassium current that controls neuronal
excitability. Mutations of the KCNQ2/KCNQ3 genes
cause BFNC, a neonatal form of epilepsy. Despite
substantial research, we do not understand yet the
mechanisms by which M-channels modulate neuronal
excitability. This book, therefore, evaluates the
impact of these channels on the excitability of
hippocampal neurons and transmitter release. It
appraises the impact of M-channels on spontaneous
excitatory/inhibitory post-synaptic currents
(sEPSCs/sIPSCs), as well as miniature EPSCs/IPSCs....