1793, Philadelphia. The nation's capital and the largest city in North America is devastated by an apparently incurable disease, cause unknown . . .

In a powerful, dramatic narrative, critically acclaimed author Jim Murphy describes the illness known as yellow fever and the toll it took on the city's residents, relating the epidemic to the major social and political events of the day and to 18th-century medical beliefs and practices. Drawing on first-hand accounts, Murphy spotlights the heroic role of Philadelphia's free blacks in combating the disease, and the Constitutional crisis...