Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will...

Ideal for marketing professionals, non-marketers, business executives, and entrepreneurs, Marketing Words of Wisdom provides guidance, tips and directions on the key marketing areas impacting future business success. Over the years, marketing consultant and brand strategist Steven Howard has jotted notes to himself on marketing concepts, ideas, philosophies, and pithy tips that he could share with clients or use in his writing. These notes have been compiled into Marketing Words of Wisdom and cover four key topic areas: Customer Retention Corporate Image and Branding Marketing Marketing As A...

This book is a collection of easy-to-read, yet thought-provoking, short memos designed to give today's corporate leaders, business owners, and entrepreneurs tips on the key marketing topics that will help you grow your businesses, retain customers, and build your corporate brands by: Leveraging the organization's most valuable asset - its corporate brand image. Creating marketing programs that follow the five Principles of a Customer-Focused Marketing Strategy and incorporate the four cornerstones of Customer Retention. Getting your entire organization to concentrate on building, earning,...

Dieselgate: The Benchmark in Corporate Cheating Scandals 2017 Distinguished Favorite Award (Leadership Books) by Independent Press Award judges The Volkswagen diesel emissions test cheating scandal and its various offshoots have had a far-reaching impact on a wide range of parties. This impact has been financial, environmental, political, and regulatory. The parties affected include car owners, Volkswagen's leadership team and employees, shareholders, car dealers, government officials, regulatory agencies, the media, the automotive industry, and even the Made-in-Germany brand....