The 21st century will witness the unprecedented marketing of therapeutic drugs developed from cannabinoids and the endocannabinoid system. Cannabinoids is a timely volume, which represents a comprehensive review of the most important issues in cannabinoid research as well as those of most likely therapeutic relevance. For the first time, the multi-faceted aspects of cannabinoid chemistry, biology and medicine are presented in one volume. Key topics of discussion:
-major families of phytocannabinoids; -pharmacological activity of phytocannabinoids;...
The 21st century will witness the unprecedented marketing of therapeutic drugs developed from cannabinoids and the endocannabinoid system. ...
The book gives an account of results obtained from experiments where grafts of neuronal, glial and other tissues as well as artificial materials were placed into the spinal cord. It attempts to evaluate the contributions made by these studies to our understanding of basic neurobiologies questions. These include factors that regulate neuronal growth during development as well as regenera tion following injury to the nervous system. The model of neural transplanta tion is also useful for the study of cell-to-cell interactions, and this applies to interactions between glial cells and neurones,...
The book gives an account of results obtained from experiments where grafts of neuronal, glial and other tissues as well as artificial materials were ...
The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the systems and cellular level, and different types of memory are implemented in several cellular changes that can interact, or work independently. From Messengers to Molecules: Memories are Made of These, follows the arguments from different research teams for their particular area of expertise. All chapters are written to stand-alone and provide an up-to-date introduction to the topic for both specialists and novices alike. As a...
The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the system...
Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their...
Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psycho...
Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer's disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.
Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degenerati...
The 21st century will witness the unprecedented marketing of therapeutic drugs developed from cannabinoids and the endocannabinoid system. Cannabinoids is a timely volume, which represents a comprehensive review of the most important issues in cannabinoid research as well as those of most likely therapeutic relevance. For the first time, the multi-faceted aspects of cannabinoid chemistry, biology and medicine are presented in one volume. Key topics of discussion:
-major families of phytocannabinoids; -pharmacological activity of phytocannabinoids;...
The 21st century will witness the unprecedented marketing of therapeutic drugs developed from cannabinoids and the endocannabinoid system. ...
eat shock proteins (HSPs), also called stress proteins, are not only induced in response to elevated temperatures, but also as a result of various stress situations, including environmental strains, viral H infection, ischemia, anoxia and oxidative stress. These stress situations trigger cellular defence mechanisms that act as an emergency system capable of combatting the toxic consequences due to the accumulation of misfolded proteins. Heat shock proteins are involved in many physiological processes, including development and differentiation, organisation of the cytoarchi tecture by binding...
eat shock proteins (HSPs), also called stress proteins, are not only induced in response to elevated temperatures, but also as a result of various str...
N aney J. Rothwell ytokine neurobiology is now a hot topic Only a few years ago C most neuroscientists were only dimly aware of cytokines and knew little about their function or biological importance. Cytokines, now a huge collection of polypeptides with diverse activities, were until quite recently, studied by those interested in the immune system, inflamma- tion, cancer or infection in peripheral tissues, and did not feature in neuroscience. For example, less than five years ago virtually no refer- ence was made to cytokines in any of the numerous abstracts at the American Society for...
N aney J. Rothwell ytokine neurobiology is now a hot topic Only a few years ago C most neuroscientists were only dimly aware of cytokines and knew li...
xidative stress refers to the cytotoxic consequences of reactive oxy- O gen species (ROS) which are generated as by-products of normal or aberrant metabolic processes that utilize molecular oxygen, or changes in protection systems. Thus, generation of ROS is a part of normal life and their interaction with host defense systems appears to exert a sig- nificant influence on the normal and abnormal functioning of the cen- tral nervous system. Oxidative stress could also be a secondary conse- quence of defects in energy metabolism involving mitochondria. A subbtle shift toward the prooxidant...
xidative stress refers to the cytotoxic consequences of reactive oxy- O gen species (ROS) which are generated as by-products of normal or aberrant met...
Claus W. Heizmann and Katharina Braun ore than 10,000 articles were published in 1994 on calcium, M 2 emphasizing the widespread interest and progress in Ca + 2 related research. This book focuses mainly on Ca + -binding pro 2 teins in the central nervous system, where Ca + ions have been found to activate fundamental processes such as release of neu rotransmitters, axonal flow, long term potentiation, cell motility, differentiation, secretion, and apoptosis. It has also been found that a number of neurodegenerative disorders have been attributed 2 1 to aberrations of intracellular Ca +...
Claus W. Heizmann and Katharina Braun ore than 10,000 articles were published in 1994 on calcium, M 2 emphasizing the widespread interest and progress...
