An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure, function, andbehaviorofalivingorganism (phenotype). At the center of this scienti?c endeavor is characterizing the bioch- ical and cellular roles of proteins, the working molecules of the machinery of life. A key to understanding of functional proteins is the knowledge of their folded str- tures in a cell, as the structures provide the basis for studying proteins' functions and functional mechanisms at the molecular level. Researchers working on structure determination have...
An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure, function, andbehaviorofaliving...
Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.
Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De...
Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and...
Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells...
This book describes advances in implantable neural stimulation technology to restore partial sight to people who are blind from retinal degnerative diseases such as age-related macular degeneration and retintis pigmentosa. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The book summarizes the state of research and clinical practice in the field and reviews the current ideas and approaches of its leading researchers and practitioners.
This book describes advances in implantable neural stimulation technology to restore partial sight to people who are blind from retinal degnerative...
This book is written from the viewpoint of a person standing with one foot in physics and the other in radiation oncology, trying to help practitioners in one field understand the problems of, and find solutions for, practitioners in the other. It should therefore be of interest both to radiation oncologists and medial physicists. The book is written in such a way that it should be of use both to beginners and to those with experience in either field - and even, perhaps, to those who are contemplating entering one of them. The goal is not to give formal and complete developments of the topics...
This book is written from the viewpoint of a person standing with one foot in physics and the other in radiation oncology, trying to help practitioner...
Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It is based on a complex self-organized mechano-chemical machine consisting of cytoskeletal filaments and molecular motors. This network is highly dynamic, but able to show precise spatial and temporal organization. The machine is regulated by a complex network of biochemical reactions coupled to force and movement generating processes.
In general, the cytoskeleton is responsible for the movement of the entire cell and for movements within...
Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It i...
This work focuses on basic concepts and recent advances in the fields of biomaterials and tissue engineering. It covers a broad spectrum of biomaterials processing and structural characteristics including discussions of biocomposites, bioglasses and issues concerning biocompatibility and tissue engineering. The text also gives the necessary theoretical background as well as a wide range of practical applications. The level and style make it accessible not only to scientific and medical researchers but also to graduate students.
This work focuses on basic concepts and recent advances in the fields of biomaterials and tissue engineering. It covers a broad spectrum of biomateria...
Learn about the many biological and medical applications of ultrashort laser pulses. The authors highlight and explain how the briefness of these laser pulses permits the tracing of even the fastest processes in photo-active bio-systems. They also present a variety of applications that rely on the high peak intensity of ultrashort laser pulses. Easy-to-follow examples cover non-linear imaging techniques, optical tomography, and laser surgery.
Learn about the many biological and medical applications of ultrashort laser pulses. The authors highlight and explain how the briefness of these l...
Bioinformatics is an interdisciplinary science which involves molecular bi- ogy, molecular chemistry, physics, mathematics, computational sciences, etc. Mostofthebooksonbiomathematicspublishedwithinthepasttenyearshave consistedofcollectionsofstandardbioinformaticsproblemsandinformational methods, andfocus mainly onthe logisticsofimplementing andmakinguse of various websites, databases, software packages and serving platforms. While these types of books do introduce some mathematical and computational methods alongside the software packages, they are lacking in a systematic and professional...
Bioinformatics is an interdisciplinary science which involves molecular bi- ogy, molecular chemistry, physics, mathematics, computational sciences, et...
