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There is often confusion over the meaning and usage of terms such as efficiency, economy, effectiveness, optimization, and perfection in biology. This book defines and discusses these concepts within a broad evolutionary perspective and considers how evolutionary pressures can affect the economy and efficiency of animals. Chapters consider biomaterials, skeletal systems, muscular function, aquatic and terrestrial locomotion, and cardiovascular systems. The result is a book of interest to all biologists, particularly those working in the field of comparative physiology and evolutionary...

Amyotrophic Lateral Sclerosis, otherwise known as Lou Gehrig's Disease, is one of several degenerative diseases of the aging nervous system. This text neatly synthesizes the recent explosion of research into this particular condition to construct a detailed and comprehensive overview. Drs. Eisen and Krieger bring their research expertise and extensive clinical experience to provide this practical and thought-provoking account. Chapters cover the epidemiology, molecular biology, and pathophysiology of ALS, as well as issues pertinent to clinical assessment and care.