Ion-Exchange Chromatography and Related Techniques

ISBN-13: 9780443153693 / Angielski

Pavel Nesterenko; Colin Poole; Yan Sun

Opis

Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.

Spis treści

1. Core concepts and milestones in the development of ion-exchange separations2. Theoretical considerations for the separation of ions3. Ion-exchange equilibria and kinetics of biopolymers4. Stationary phases for ion separations by ion-exchange chromatography5. Stationary phases for the separation of biopolymers by ion-exchange chromatography6. Ion-exchange separations on grafted and surface-modified polymers7. Liquid ion-exchangers8. Ion-exchange membranes9. Ion-exclusion chromatography10. Ion-chelation chromatography11. Displacement chromatography with ion exchangers12. Instrument platforms for ion chromatography13. Ion detection14. Instrument platforms for large-scale ion-exchange separations15. Method development for ion-exchange chromatography16. Sample preparation for ion-exchange separations17. Separation of ions by ion chromatography18. Applications of ion chromatography in environmental analysis19. Applications of ion-exchange chromatography in the food industry20. Applications of ion-exchange chromatography in hydrometallurgy21. Separation of saccharides by ion-exchange chromatography22. Separation of oligonucleotides by ion-exchange chromatography23. Separation of amino acids, peptides, and proteins by ion-exchange chromatography24. Separation of proteins by mixed-mode chromatography25. Process modeling of protein separations by ion-exchange chromatography26. Applications of Ion-exchange chromatography for the purification of antibodies27. Continuous chromatography for protein polishing and enrichment using ion exchange28. Separation of bio-particles by ion-exchange chromatography29. Separation of isotopes by ion-exchange and ion-chelation chromatography