1. Purpose of this edition (Scope of textbook) 2. Bioprocess Development: An Interdisciplinary Challenge PART 1: FUNDAMENTAL CONCEPTS 3. Microbiology and Biochemistry 4. Material Balances 5. Energy Balances 6. Enzyme and Cell Growth Kinetics PART 2: BIOREACTORS AND TRANSPORT 7. Bioreactors 8. Mixing 9. Bioreactor Mass Transfer 10. Bioreactor Heat Transfer PART 3: PROCESS INTEGRATION AND APPLICATION 11. Unit Operations/Downstream Processing 12. Genetic and Evolutionary Engineering of Organisms for Bioprocessing 13. Process Engineering and Design of Bioprocesses