Wyniki wyszukiwania:

This volume provides a compilation of the main principles of signal transduction mechanisms. The reader will become familiar with the most recent developments on:
- the structure and function of heterotrimeric G-proteins and their receptors;
- the small GTPases Ras, Rho, Rab and Arf;
- EGF receptor, Ca2+ and protein kinase C;
- phosphoinositide kinases (PI-3 kinases);
- phospholipases C and D;
- ceramides and possible modulators of apoptosis;
- transcription factors and gene activation;
- multidrug resistance transporters.

Providing a survey on current research in eukaryotic signal transduction, some of the topics covered are, the biochemistry and biophysics of cell surface receptors, G-protein mediated signalling pathways, regulation of cyclic AMP, Ca2+, inositol phosphate pathways, the structure and regulation of receptors which are tyrosine protein kinases, and cellular responses to integrated signals.