UV AND HPLC Method Development and Method Validation of Nevirapine : UV AND HPLC Method Development and Validation of Nevirapine in Bulk and Pharmaceutical dosage forms

ISBN-13: 9786200218094 / Angielski

Tirthankar Choudhury

Opis

This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and precision. The proposed method is simple, economical, fast, accurate and precise, hence can be applied for routine quality control of nevirapine in bulk and tablet dosage forms.

O autorze

Choudhury, Tirthankar
Dr. (Prof.) Tirthankar Choudhury had his M. Pharm (Pharm. Chemistry) in 2008 and Ph.D.(Pharmaceutical Science) in 2012. Till now he had 11 years of teaching experience along with several paper publications. Now he is associated with Editorial and Advisory Boards of many journals.Hoping towards his wide acceptance in Pharmacy profession.