The Exstrophy--Epispadias Complex: Research Concepts and Clinical Applications

ISBN-13: 9780306461286 / Angielski / Twarda / 1999 / 252 str.

John P. Gearhart; Ranjiv Mathews; John P. Gearhart

Opis

The undertaking of the treatment of an infant born with bladder exstrophy is one of the most weighty responsibilities that can fall upon the shoulders of the reconstructive sur geon. The modern treatment of a child born with bladder exstrophy began in the mid- 1970's with the widespread application of staged reconstruction. This approach has consistently yielded very good results in several series. However, as in all serious congeni tal birth defects, there is certainly room for advancement. Issues such as the routine use of osteotomy, timing and type of epispadias repair, combining bladder closure with epispadias repair, the approach to the small bladder, and the management of a failed exstrophy still remain. This National Institute of Health/Na tional Kidney Foundation/Johns Hopkins-sponsored seminar was an attempt to bring ex perts in the field of pediatric orthopedic surgery, pediatric urology, pediatric surgery, adult urology, and basic science together to share their experiences in an attempt to foster new clinical and basic science research communications between the participants. If these col laborations result, then this first international meeting will have been successful. The editors would like to thank all of the contributors for their timely and complete submissions. John P. Gearhart, M.D. Ranjiv Mathews, M.D. vii CONTENTS 1. The Embryology and Epidemiology of Bladder Exstrophy ................. ."

Spis treści

1. Embryology and Epidemiology of Bladder Exstrophy; B. Slaughenhaupt. 2. Prenatal Diagnosis of Classic Bladder Exstrophy and Cloacal Exstrophy; R. Sanders. 3. Bony Pelvic Anatomy in Bladder Exstrohy; P. Sponseller, M. Jani. 4. Bladder Muscle Physiology in the Exstrophy Patient; J. Gosling, et al. 5. The Response of the Bladder Smooth Muscle to Increased Bladder Neck Resistance; E. Macarak. 6. Muscarinic Receptor Content in Exstrophied Bladders; E. Shapiro. 7. Bladder Compositon in Exstrophy at Various Stages of Reconstruction; D. Peppas. 8. Collagen Subtypes in Exstrophied Bladders; B. Lee. 9. A Large Animal Model of Bladder Exstrophy - Observations on Smooth Muscle, Collagen Content and Function; B. Slaughenhaupt. 10. Tissue Engineering Techniques for Closure of Bladder Exstrophy - An Experimental Animal Model; A. Atala. 11. Surgical Principles in the Closure of Bladder Exstrophy; J. Gearhart, R. Mathews. 12. Use of Osteotomy in the Treatment of Bladder Exstrophy; P. Sponseller, M. Jani. 13. Bladder Exstrophy Closure without Osteotomies; J. Duckett, H. McC Snyder. 14. Bladder Exstrophy Closure with Pubic Ramotomies; P. Frey. 15. The Failed Exstrophy Closure: Strategy for Management - The Johns Hopkins Approach; J. Gearhart, R. Mathews. 16. Applications of Ureterosigmoidostomy in Bladder Exstrophy; M. Fisch. 17. Indications and Types of Augmentation in Bladder Exstrophy; S. Docimo. 18. Alternative Forms of Management of Bladder Exstrophy; S. Arap. 19. Penile Length in Exstrophy/Epispadias; R. Silver. 20. The Mitchell Epispadias Repair; M. Mitchell. 21. The Cantwell-Ransley Epispadias Repair; J. Ben-Chaim. 22. The Impact of Urodynamics for Incontinence in Children with Exstrophy; S. Bauer. 23. The Use of Submucosal Collagen in the Small Bladder Associated with Bladder Exstrophy; P. Caoine. 24. Bladder Neck Reconstruction and Subsequent Care; R. Jeffs. 25. The Psychological Impact of Exstrophy-Epispadias Complex; W. Reiner. 26. Long-Term Results of Bladder Exstrophy &endash; The Johns Hopkins Experience; J. Ben-Chaim. 27. Long-Term Results of Bladder Exstrophy &endash; The London Experience; C. Woodhouse. 28. Long-Term Results of Bladder Exstrophy &endash; The Mainz Experience; M. Fisch. 29. Fertility in the Male Exstrophy Patient; T. Hensle. 30. Anatomy and Presentation of Cloacal Exstrophy; D. Husmann. 31. Management of Cloacal Exstrophy; J. Woodard. 32. Indications and Types of Augmentation in Cloacal Exstrophy; M. Mitchell. 33. Long-Term Follow-Up of Patients with Cloacal Exstrophy; W.H. Hendren.