The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs

ISBN-13: 9780849327919 / Angielski / Twarda / 1998 / 400 str.

Hans Christian Korting; Monika Schafer-Korting; M. Schdfer-Korting

Opis

The use of drugs as remedies for various types of diseases has a long tradition, but the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the whole picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data which should optimize the clinician's decision making in selecting effective, low-risk drug treatments.

Spis treści

The Role and Analysis of Benefit and Risk in the Development of New Drugs. Prediction of the Benefit/Risk Ratio from In Vitro Data. Evaluation of Therapeutic Benefits and Toxicological Risks Using Structure-Activity Relational Expert Systems. Improving the Therapeutic Index Through Unusual Routes of Application: Intra-Arterial Treatment of Liver Metastases. Establishing the Benefit/Risk Ration with Combination Drugs. Improving the Therapeutic Index of Antineoplastic Agents through Additional Drugs. Antihypertensive Agents. Diueretics. Anti-Diabetic Drugs. Anticonvulsant Drugs and Drugs for Parkinson's Disease. Antihistamines and Antiserotonins. Cytokines and Immunomodulators. Non-Opioid Analgesics and Anti-Inflammatory Agents. Toxicity Profile of Liposomal Anthacyclines. Antibacterial Agents. Antiviral Agents. Drugs Used in Reproductive Endocrinology. Nicotine Preparations in Smoking. Systemic Drugs for Skin Diseases. Topical Liposome Drugs. Topical Glucocorticoids. Index.

O autorze

Korting, Hans C. | Schafer-Korting, M.